Department of Cranio-Maxillofacial Surgery, University Hospital Muenster, 48149 Muenster, Germany.
Department of Prosthodontics, School of Dentistry, University of São Paulo, São Paulo 0508-000, Brazil.
Int J Environ Res Public Health. 2020 Dec 11;17(24):9282. doi: 10.3390/ijerph17249282.
The aim of this study was to assess trabecular bone morphology via magnetic-resonance imaging (MRI) using microcomputed tomography (µCT) as the control group. Porcine bone samples were scanned with T1-weighted turbo spin echo sequence imaging, using TR 25 ms, TE 3.5 ms, FOV 100 × 100 × 90, voxel size 0.22 × 0.22 × 0.50 mm, and scan time of 11:18. µCT was used as the control group with 80 kV, 125 mA, and a voxel size of 16 µm. The trabecular bone was segmented on the basis of a reference threshold value and morphological parameters. Bone volume (BV), Bone-volume fraction (BvTv), Bone specific surface (BsBv), trabecular thickness (TbTh), and trabecular separation (TbSp) were evaluated. Paired -test and Pearson correlation test were performed at = 0.05. MRI overestimated BV, BvTv, TbTh, and TbSp values. BsBv was the only parameter that was underestimated by MRI. High statistical correlation (r = 0.826; < 0.05) was found for BV measurements. Within the limitations of this study, MRI overestimated trabecular bone parameters, but with a statistically significant fixed linear offset.
本研究旨在通过磁共振成像（MRI）评估小梁骨形态，以微计算机断层扫描（µCT）作为对照组。使用 T1 加权涡轮自旋回波序列成像对猪骨样本进行扫描，TR 为 25 ms，TE 为 3.5 ms，视野为 100×100×90，体素大小为 0.22×0.22×0.50 mm，扫描时间为 11：18。µCT 作为对照组，管电压为 80 kV，管电流为 125 mA，体素大小为 16 µm。基于参考阈值和形态学参数对小梁骨进行分割。评估骨体积（BV）、骨体积分数（BvTv）、骨比表面积（BsBv）、小梁厚度（TbTh）和小梁间隔（TbSp）。在 = 0.05 时进行配对检验和 Pearson 相关检验。MRI 高估了 BV、BvTv、TbTh 和 TbSp 值。只有 BsBv 是 MRI 低估的参数。BV 测量值的相关性很高（r = 0.826；<0.05）。
在本研究的限制范围内，MRI 高估了小梁骨参数，但存在统计学上显著的固定线性偏移。
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