Liu Gang, Chia Chin-Hsuan, Cao Yue, Tang Xin-Wei, Tian Shan, Shen Xue-Yan, Chen Ying, Lu Rong-Rong, Wu Jun-Fa, Wu Yi
Department of Rehabilitation Medicine, Huashan Hospital, Fudan University, Shanghai, China.
Front Neurol. 2020 Nov 24;11:544912. doi: 10.3389/fneur.2020.544912. eCollection 2020.
To study differential post-stroke changes of excitability of spinal motor neurons innervating a group of antagonist muscles of ankle and their effects on foot inversion. F waves in tibialis anterior (TA) and peroneus muscles (PN) were recorded. The condition of spasticity and foot inversion in stroke patients were also evaluated. The differences of F wave parameters between patients and healthy controls (HC), as well as TA and PN, were investigated. There were natural differences in the persistence of the F waves (Fp) and F/M amplitude ratio (F/M) between TA and PN in HC. Stroke patients showed significantly higher F/M in TA and PN, while there was no difference in Fp comparing to HC. The natural differences in F wave parameters between TA and PN were differentially retained after stroke. The natural difference of the two muscles in Fp remained unchanged and the F/M difference disappeared in those without spasticity or foot inversion, while the Fp difference disappeared and the F/M difference remained in those with spasticity or foot inversion. Based on the natural difference of the number and size of spinal motor neurons innervating TA and PN, their excitability may change differently according to the severity of the stroke, which may be the reason of foot inversion.
研究中风后支配踝关节一组拮抗肌的脊髓运动神经元兴奋性的差异变化及其对足内翻的影响。记录胫前肌（TA）和腓骨肌（PN）的F波。评估中风患者的痉挛状态和足内翻情况。研究患者与健康对照（HC）之间以及TA和PN之间F波参数的差异。HC中TA和PN的F波持续时间（Fp）和F/M振幅比（F/M）存在自然差异。中风患者TA和PN的F/M显著更高，而与HC相比，Fp无差异。中风后TA和PN之间F波参数的自然差异被不同程度地保留。在无痉挛或足内翻的患者中，两块肌肉在Fp上的自然差异保持不变，F/M差异消失；而在有痉挛或足内翻的患者中，Fp差异消失，F/M差异保持。基于支配TA和PN的脊髓运动神经元数量和大小的自然差异，它们的兴奋性可能根据中风严重程度而发生不同变化，这可能是足内翻的原因。
