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洞察美国慢性疼痛:处方阿片类药物滥用和误用问卷(POMAQ)验证研究的描述性结果。

Insight into chronic pain in the United States: descriptive results from the Prescription Opioid Misuse and Abuse Questionnaire (POMAQ) validation study.

机构信息

Evidera, Bethesda, MD, USA.

Formerly Pfizer Inc., New York, NY, USA.

出版信息

Curr Med Res Opin. 2021 Mar;37(3):483-492. doi: 10.1080/03007995.2020.1865889. Epub 2021 Jan 18.

DOI:10.1080/03007995.2020.1865889
PMID:33331191
Abstract

OBJECTIVE

A chronic pain patient sample living in the United States who participated in a cross-sectional study to evaluate the validity and reproducibility of the Prescription Opioid Misuse and Abuse Questionnaire is characterized.

METHODS

Patients with chronic pain identified through electronic medical records as refilling at least one opioid prescription within the prior 3 months were recruited from five United States Department of Defense Military Health System clinics. Patients completed the Prescription Opioid Misuse and Abuse Questionnaire, Brief Pain Inventory-Short Form, Medical Outcomes Study: 36-item Short Form, and sociodemographic questions online. Clinical characteristics and electronic medical records for 1 year prior to consent were collected.

RESULTS

809 (86.2%) participants completed the Prescription Opioid Misuse and Abuse Questionnaire. Mean (± standard deviation) age was 55.4 ± 12.7 years; the majority female (55.5%) and white (74.8%). Mean duration of chronic pain was 14.7 ± 10.5 years; the most common pain conditions were lower back pain (76.6%), neck or shoulder pain (60.3%), and osteoarthritis (38.7%). The most commonly prescribed opioids were oxycodone (35.7%), tramadol (34.5%), and hydrocodone (26.9%); 54.8% took one opioid, 44.9% took 2 or more opioids.

DISCUSSION

Participants' health status was poor; pain severity and interference were moderate. Electronic medical record data revealed high healthcare resource utilization. This chronic pain population was severely impacted by their pain condition(s).

摘要

目的

本研究对参与一项横断面研究的美国慢性疼痛患者样本进行了描述,该研究旨在评估处方阿片类药物滥用和误用问卷的有效性和可重复性。

方法

从美国五家国防部医疗系统诊所招募了通过电子病历确定的在过去 3 个月内至少有一次阿片类药物处方再配药的慢性疼痛患者。患者在线完成了处方阿片类药物滥用和误用问卷、简明疼痛量表-短表、医疗结局研究 36 项简明健康调查问卷和社会人口学问题。在同意前的 1 年内收集了临床特征和电子病历。

结果

809 名(86.2%)参与者完成了处方阿片类药物滥用和误用问卷。平均(±标准差)年龄为 55.4±12.7 岁;大多数为女性(55.5%)和白人(74.8%)。慢性疼痛的平均持续时间为 14.7±10.5 年;最常见的疼痛病症为下腰痛(76.6%)、颈肩部疼痛(60.3%)和骨关节炎(38.7%)。最常开的阿片类药物为羟考酮(35.7%)、曲马多(34.5%)和氢可酮(26.9%);54.8%的患者使用一种阿片类药物,44.9%的患者使用 2 种或以上阿片类药物。

讨论

参与者的健康状况较差;疼痛严重程度和干扰程度为中度。电子病历数据显示,医疗资源的利用度较高。该慢性疼痛人群深受其疼痛状况的影响。

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