Buitrago-Ricaurte Natalia, Cintra Fátima, Silva Gisele Sampaio
Universidade Federal de São Paulo, Department of Neurology, São Paulo SP, Brazil.
Universidade Federal de São Paulo, Department of Cardiology, São Paulo SP, Brazil.
Arq Neuropsiquiatr. 2020 Nov;78(11):724-732. doi: 10.1590/0004-282X20200087.
Stroke is one of the leading causes of mortality and disability worldwide. Autonomic dysfunction after ischemic stroke is frequently associated with cardiac complications and high mortality. The brain-heart axis is a good model for understanding autonomic interaction between the autonomic central network and the cardiovascular system. Heart rate variability (HRV) analysis is a non-invasive approach for understanding cardiac autonomic regulation. In stroke patients, HRV parameters are altered in the acute and chronic stages of the disease, having a prognostic value. In this literature review we summarize the main concepts about the autonomic nervous system and HRV as autonomic biomarkers in ischemic stroke.
中风是全球范围内导致死亡和残疾的主要原因之一。缺血性中风后的自主神经功能障碍常与心脏并发症和高死亡率相关。脑-心轴是理解自主神经中枢网络与心血管系统之间自主神经相互作用的良好模型。心率变异性（HRV）分析是一种用于理解心脏自主神经调节的非侵入性方法。在中风患者中，HRV参数在疾病的急性期和慢性期都会发生改变，具有预后价值。在这篇文献综述中，我们总结了关于自主神经系统和HRV作为缺血性中风自主生物标志物的主要概念。
