Department of Psychiatry, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Department of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan.
Int J Environ Res Public Health. 2022 Apr 25;19(9):5230. doi: 10.3390/ijerph19095230.
The aims of this study were to investigate the efficacy of heart rate variability biofeedback (HRVBFB) intervention in terms of reducing craving, severity of dependence, and rate of positive methamphetamine urine testing in men taking part in a methamphetamine use disorder outpatient treatment program. Sixty-one adult men received either HRVBFB treatment plus treatment as usual (TAU) over four weeks or TAU only. Men receiving HRVBFB showed significantly greater reductions in craving, dependence severity, and the rate of positive methamphetamine urine testing at the end of the intervention and four weeks of follow-up. The analyses further showed that the levels of craving and dependence severity at treatment entry were predictive of changes in craving and dependence severity at the end of treatment and follow-up, respectively. The baseline status of a positive methamphetamine urine test only predicted a positive methamphetamine urine test at the end of treatment, not at the end of the follow-up period. Our results showed HRVBFB intervention has merits as an adjunct treatment to ameliorate cravings and reduce the severity of dependence experienced by persons with methamphetamine use disorder. An added value of HRVBFB intervention is the fact that it can be easily and affordably implemented in everyday life.
本研究旨在探究心率变异性生物反馈（HRVBFB）干预在减少男性参与治疗门诊治疗方案的阿片类药物使用障碍的觅药冲动、依赖严重程度和阳性阿片类药物尿液检测率方面的效果。61 名成年男性接受了为期四周的 HRVBFB 治疗加常规治疗（TAU）或仅 TAU。接受 HRVBFB 的男性在干预结束时和随访四周时，觅药冲动、依赖严重程度和阳性阿片类药物尿液检测率显著降低。分析进一步表明，治疗开始时的觅药冲动和依赖严重程度分别预测了治疗结束时和随访结束时的觅药冲动和依赖严重程度的变化。基线阳性阿片类药物尿液检测仅预测治疗结束时的阳性阿片类药物尿液检测，而不是随访结束时的阳性阿片类药物尿液检测。我们的研究结果表明，HRVBFB 干预作为一种辅助治疗方法，在改善阿片类药物使用障碍患者的觅药冲动和减轻依赖严重程度方面具有优势。HRVBFB 干预的一个附加价值在于它可以在日常生活中轻松且经济实惠地实施。
