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[新型冠状病毒肺炎患者的皮肤病变]

[Cutaneous lesions in COVID-19 patients].

作者信息

Çiftçi Z, Clabbers J M K, Galimont-Collen A F S, Gostyński A

机构信息

Nederlandse Vereniging voor Dermatologie en Venereologie, Utrecht.

Maastricht UMC+, afd. Dermatologie, Maastricht.

出版信息

Ned Tijdschr Geneeskd. 2020 Dec 3;164:D5443.

Abstract

Aside from the typical respiratory symptoms resulting from an infection with SARS-CoV-2, there are reports of cutaneous lesions in patients diagnosed with a SARS-CoV-2 infection. There are reports of multiple groups of skin lesions presenting in different stages of this diagnosis. The most common reported groups are chilblains, vesicular eruptions, morbilliformexanthems, acute urticaria and livedo. It is unlikely that all these groups of skin lesions are distinctive of an infection with SARS-CoV-2. Chilblains of new onset, however, could possibly be a distinctive symptom of a mild/asymptomatic infection with SARS-CoV-2. It is recommended to consider an infection with SARS-CoV-2 in the differential diagnosis in patients presenting with these groups of skin lesions. Consider testing for SARS-CoV-2 and consult the dermatologist if needed, especially in case of chilblains, to ensure histopathological evaluation of the skin lesions to increase knowledge of the underlying pathophysiology.

摘要

除了感染新型冠状病毒导致的典型呼吸道症状外,有报告称确诊新型冠状病毒感染的患者出现了皮肤病变。有报告指出,在该诊断的不同阶段出现了多组皮肤病变。报告中最常见的几组是冻疮、水疱疹、麻疹样皮疹、急性荨麻疹和青斑。所有这些皮肤病变组不太可能都是新型冠状病毒感染所特有的。然而,新发冻疮可能是新型冠状病毒轻度/无症状感染的一个独特症状。对于出现这些皮肤病变组的患者,建议在鉴别诊断中考虑新型冠状病毒感染。考虑进行新型冠状病毒检测,如有需要咨询皮肤科医生,尤其是出现冻疮的情况,以确保对皮肤病变进行组织病理学评估,增加对潜在病理生理学的了解。

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