Department of Dermatology, Keck School of Medicine, University of Southern California, Los Angeles, CA.
Dermatol Online J. 2021 Jan 15;27(1):13030/qt2m54r7nv.
The severe acute respiratory syndrome coronavirus two (SARS-CoV-2), which causes the 2019 coronavirus disease (COVID-19), has infected patients worldwide. Physicians have increasingly identified cutaneous findings as a significant clinical manifestation of COVID-19. In this review, we describe the clinical presentation, onset, duration, associated symptoms, treatment, and outcome of cutaneous manifestations thus far reported to be related to COVID-19. We have included data from 63 studies and subdivided reported cutaneous manifestations into the categories of viral exanthem, urticarial, vesicular, chilblains/chilblains-like, non-chilblains vasculopathy-related, pityriasis rosea-like, erythema multiforme-like, Kawasaki/Kawasaki-like disease, and others. Physicians should be aware of the known common cutaneous manifestations of COVID-19 and future research is required to better understand the pathophysiology and prognosis of each COVID-19-related skin manifestation.
严重急性呼吸综合征冠状病毒 2 型(SARS-CoV-2)可引起 2019 年冠状病毒病(COVID-19),已在全球范围内感染患者。医生越来越多地发现皮肤表现是 COVID-19 的一个重要临床表现。在这篇综述中,我们描述了迄今为止与 COVID-19 相关的皮肤表现的临床特征、发病、持续时间、相关症状、治疗和结局。我们纳入了 63 项研究的数据,并将报告的皮肤表现分为病毒性出疹、荨麻疹、水疱、冻疮样/冻疮样、非冻疮样血管病变相关、玫瑰糠疹样、多形红斑样、川崎病/川崎病样疾病和其他。医生应了解 COVID-19 的已知常见皮肤表现,需要进一步研究以更好地了解每种 COVID-19 相关皮肤表现的病理生理学和预后。