New York City Health + Hospitals, Office of Population Health, New York, New York, United States of America.
New York City Health + Hospitals/North Central Bronx, New York, New York, United States of America.
PLoS One. 2020 Dec 17;15(12):e0243027. doi: 10.1371/journal.pone.0243027. eCollection 2020.
New York City (NYC) bore the greatest burden of COVID-19 in the United States early in the pandemic. In this case series, we describe characteristics and outcomes of racially and ethnically diverse patients tested for and hospitalized with COVID-19 in New York City's public hospital system.
We reviewed the electronic health records of all patients who received a SARS-CoV-2 test between March 5 and April 9, 2020, with follow up through April 16, 2020. The primary outcomes were a positive test, hospitalization, and death. Demographics and comorbidities were also assessed.
22254 patients were tested for SARS-CoV-2. 13442 (61%) were positive; among those, the median age was 52.7 years (interquartile range [IQR] 39.5-64.5), 7481 (56%) were male, 3518 (26%) were Black, and 4593 (34%) were Hispanic. Nearly half (4669, 46%) had at least one chronic disease (27% diabetes, 30% hypertension, and 21% cardiovascular disease). Of those testing positive, 6248 (46%) were hospitalized. The median age was 61.6 years (IQR 49.7-72.9); 3851 (62%) were male, 1950 (31%) were Black, and 2102 (34%) were Hispanic. More than half (3269, 53%) had at least one chronic disease (33% diabetes, 37% hypertension, 24% cardiovascular disease, 11% chronic kidney disease). 1724 (28%) hospitalized patients died. The median age was 71.0 years (IQR 60.0, 80.9); 1087 (63%) were male, 506 (29%) were Black, and 528 (31%) were Hispanic. Chronic diseases were common (35% diabetes, 37% hypertension, 28% cardiovascular disease, 15% chronic kidney disease). Male sex, older age, diabetes, cardiac history, and chronic kidney disease were significantly associated with testing positive, hospitalization, and death. Racial/ethnic disparities were observed across all outcomes.
This is the largest and most racially/ethnically diverse case series of patients tested and hospitalized for COVID-19 in New York City to date. Our findings highlight disparities in outcomes that can inform prevention and testing recommendations.
纽约市(NYC)在大流行早期是美国 COVID-19 负担最重的地区。在本病例系列中,我们描述了在纽约市公立医院系统中接受 COVID-19 检测和住院治疗的不同种族和族裔患者的特征和结局。
我们回顾了 2020 年 3 月 5 日至 4 月 9 日期间接受 SARS-CoV-2 检测的所有患者的电子健康记录,并在 2020 年 4 月 16 日前进行随访。主要结局为检测阳性、住院和死亡。还评估了人口统计学和合并症。
共有 22254 名患者接受了 SARS-CoV-2 检测。13442 名(61%)检测结果为阳性;其中,中位年龄为 52.7 岁(四分位距 [IQR] 39.5-64.5),7481 名(56%)为男性,3518 名(26%)为黑人,4593 名(34%)为西班牙裔。近一半(4669 名,46%)至少患有一种慢性病(27%糖尿病,30%高血压,21%心血管疾病)。在检测结果阳性的患者中,有 6248 名(46%)住院。中位年龄为 61.6 岁(IQR 49.7-72.9);3851 名(62%)为男性,1950 名(31%)为黑人,2102 名(34%)为西班牙裔。超过一半(3269 名,53%)至少患有一种慢性病(33%糖尿病,37%高血压,24%心血管疾病,11%慢性肾脏病)。1724 名(28%)住院患者死亡。中位年龄为 71.0 岁(IQR 60.0, 80.9);1087 名(63%)为男性,506 名(29%)为黑人,528 名(31%)为西班牙裔。慢性病很常见(35%糖尿病,37%高血压,28%心血管疾病,15%慢性肾脏病)。男性、年龄较大、糖尿病、心脏病史和慢性肾脏病与检测阳性、住院和死亡显著相关。在所有结局中都观察到种族/族裔差异。
这是迄今为止纽约市最大和种族/族裔最多样化的 COVID-19 患者检测和住院病例系列。我们的研究结果突出了可影响预防和检测建议的结局差异。