Department of Biomedical Engineering, Texas A&M University, College Station, TX 77843, USA.
Analyst. 2021 Feb 21;146(4):1253-1259. doi: 10.1039/d0an01962c. Epub 2020 Dec 17.
Chemical imaging of calcifications was demonstrated in the depth of a tissue. Using long wavelength excitation, broadband coherent anti-Stokes Raman scattering and hierarchical cluster analysis, imaging and chemical analysis were performed 2 mm below the skin level in a model system. Applications to breast cancer diagnostics and imaging are discussed together with the methods to further extend the depth and improve the spatial resolution of chemical imaging.
在组织深处展示了钙化的化学成像。使用长波长激发、宽带相干反斯托克斯拉曼散射和层次聚类分析，在模型系统中在皮肤以下 2 毫米处进行了成像和化学分析。讨论了这些方法在乳腺癌诊断和成像中的应用，以及进一步扩展化学成像深度和提高空间分辨率的方法。
