Li Z A, Zhao R L, Zhao F F, Shu W, Duan J W, Li L, Li M L, Amaerjiang Nubiya, Xiao H D, Hu Y F
Department of Child, Adolescent Health and Maternal Care, School of Public Health, Capital Medical University, Beijing 100069, China.
Department of School Health, Shunyi District Center for Disease Control and Prevention, Beijing 101300, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2020 Dec 6;54(12):1378-1382. doi: 10.3760/cma.j.cn112150-20200612-00875.
To explore sex difference in height growth and blood pressure (BP) change among Beijing school-age children and adolescents. Using physical examination data of 70 769 school-age children and adolescents from primary to high school during 2009-2018 in Shunyi District, a longitudinal dataset was formed with completed anthropometrical measurements of height and blood pressure (BP) after individual information linkage. Age-specific height, BP, growth rate of height and BP as well BP growth rate based on age at peak height velocity (PHA) were calculated. Linear mixed-effects model was used to identify sex disparity in the growth rates of height and BP. Height and BP increased with age in both boys and girls, and the mean height and BP of boys were always higher than those of girls, except age group from 10 to 11 years. Sex disparity existed in growth rates of height and BP (<0.001), which was demonstrated by the interaction item of"sex x age"in linear mixed-effects model. The PHA of boys was 12 years old, which was 2 years later than that of girls, about 10 years old. The curves of BP growth rate with age showed double peaks in both boys and girls. Boys reached the peak BP velocity at 13 years old, 3 years lagging behind that of girls who reached the peak at 10 years old. However, the peak of height and BP velocity of boys were higher than that of girls. The change of BP was highly synchronized in time with the increase of height, after adjusting for the growth rate of height by PHA. BP velocity increased with age before onset of puberty till PHA and then declined. Sex disparity in height growth and BP change among school-age children and adolescents is persistent and significant and the change of BP is highly synchronized in time with the increase of height.
探讨北京学龄儿童和青少年身高增长及血压变化的性别差异。利用顺义区2009 - 2018年70769名从小学到高中的学龄儿童和青少年的体检数据,通过个体信息关联形成了一个包含身高和血压完整人体测量数据的纵向数据集。计算了特定年龄的身高、血压、身高增长率和血压增长率以及基于身高增长速度峰值(PHA)年龄的血压增长率。采用线性混合效应模型来识别身高和血压增长率的性别差异。男孩和女孩的身高和血压均随年龄增长,除了10至11岁年龄组外,男孩的平均身高和血压始终高于女孩。身高和血压增长率存在性别差异(<0.001),这在线性混合效应模型中的“性别×年龄”交互项中得到体现。男孩的PHA为12岁,比女孩约10岁晚2年。男孩和女孩的血压增长率随年龄变化的曲线均呈现双峰。男孩在13岁达到血压增长速度峰值,比在10岁达到峰值的女孩滞后3年。然而,男孩身高和血压增长速度的峰值高于女孩。在根据PHA调整身高增长率后,血压变化与身高增加在时间上高度同步。青春期开始前直至PHA,血压增长速度随年龄增加,之后下降。学龄儿童和青少年身高增长及血压变化的性别差异持续且显著,血压变化与身高增加在时间上高度同步。