电子烟吸食对视网膜微循环的影响：黄斑无血管区扩大。
The effect of electronic cigarette smoking on retinal microcirculation: Enlargement of the foveal avascular zone.
作者信息
Kalayci Mustafa, Cetinkaya Ersan, Suren Elcin, Yigit Kenan, Duman Fulya, Erol Muhammet Kazim
机构信息
University of Health Sciences, Antalya Training and Research Hospital, Department of Ophthalmology, Antalya, Turkey.
University of Health Sciences, Antalya Training and Research Hospital, Department of Ophthalmology, Antalya, Turkey.
出版信息
Photodiagnosis Photodyn Ther. 2020 Dec;32:102068. doi: 10.1016/j.pdpdt.2020.102068. Epub 2020 Oct 23.
BACKGROUND
To evaluate retinal microcirculation in electronic cigarette (e-cigarette) smokers using optical coherence tomography angiography (OCTA).
METHODS
OCTA measurements were performed on the left eyes of 21 e-cigarette smokers and 21 healthy controls. Superficial and deep foveal, perifoveal and parafoveal vessel densities, outer retina and choriocapillaris flow area, foveal avascular zone (FAZ), and central macular thickness were evaluated in both groups.
RESULTS
The FAZ area was larger in e-cigarette smokers than the control group, and the difference was statistically significant (p = 0.003). The superficial foveal, superficial total, deep foveal and deep total vascular densities were significantly lower in the e-cigarette group compared to the control group (p = 0.011, p = 0.012, p = 0.022, and p = 0.041, respectively). Central macular thickness was lower in the e-cigarette smokers but the difference was not statistically significant (p = 0.678).
CONCLUSIONS
E-cigarette smoking causes enlargement of the FAZ area and decreases vascular densities.
背景
使用光学相干断层扫描血管造影（OCTA）评估电子烟吸烟者的视网膜微循环。
方法
对21名电子烟吸烟者和21名健康对照者的左眼进行OCTA测量。评估两组的浅表和深层中央凹、中央凹周围和黄斑旁血管密度、视网膜外层和脉络膜毛细血管血流面积、中央凹无血管区（FAZ）以及黄斑中心厚度。
结果
电子烟吸烟者的FAZ面积大于对照组，差异具有统计学意义（p = 0.003）。与对照组相比，电子烟组的浅表中央凹、浅表总体、深层中央凹和深层总体血管密度显著降低（分别为p = 0.011、p = 0.012、p = 0.022和p = 0.041）。电子烟吸烟者的黄斑中心厚度较低，但差异无统计学意义（p = 0.678）。
结论
吸电子烟会导致FAZ面积增大并降低血管密度。
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