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颈静脉孔副神经节瘤:术前经导管颗粒栓塞术

Jugular foramen paragangliomas: preoperative transcatheter particle embolization.

作者信息

Ishak Charbel, Danda Varun

机构信息

Department of Interventional Radiology at Envision BronxCare Health System, Affiliate of Icahn School of Medicine at Sinai, NY, USA.

Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.

出版信息

J Cerebrovasc Endovasc Neurosurg. 2020 Dec;22(4):273-281. doi: 10.7461/jcen.2020.E2019.09.033. Epub 2020 Dec 18.

Abstract

Jugular foramen paragangliomas (JFP) are benign tumors of neural crest origin that are located along the temporal bone in the region of the jugular bulb and middle ear. The optimal management of these lesions includes surgical excision with or without preoperative embolization as well as stereotactic radiotherapy. The use of preoperative embolization in the treatment of JFP has shown great promise to bridge patients to surgery by diminishing complication rates and decreasing intraoperative bleeding. We present three successful polyvinyl alcohol (PVA) particle embolizations of patients presenting with symptomatic JFPs. All patients recovered completely in the short term with no bleeding during or after resection of paragangliomas and they were discharged free of their presenting symptoms. Early clinical and imaging diagnosis followed by adequate treatment including preoperative transcatheter particle embolization and surgical or radiosurgical interventions can lead to excellent outcomes.

摘要

颈静脉孔副神经节瘤(JFP)是起源于神经嵴的良性肿瘤,位于颞骨的颈静脉球和中耳区域。这些病变的最佳治疗方法包括手术切除(可术前栓塞或不栓塞)以及立体定向放射治疗。术前栓塞用于治疗JFP已显示出巨大前景,可通过降低并发症发生率和减少术中出血,为患者接受手术创造条件。我们介绍了3例有症状JFP患者成功接受聚乙烯醇(PVA)颗粒栓塞治疗的病例。所有患者短期内均完全康复,副神经节瘤切除术中及术后均无出血,且出院时症状消失。早期临床和影像学诊断,随后进行包括术前经导管颗粒栓塞及手术或放射外科干预在内的充分治疗,可带来良好预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8fb/7820265/252142039858/jcen-2020-e2019-09-033f1.jpg

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