Garayzade Rana, Leicht Jakob, Eckardt Niklas, Koscielny Sven, Mayer Thomas E
Department of Neuroradiology, Institute of Diagnostic and Interventional Radiology, University Hospital Jena, 07747 Jena, Germany.
Department of Otorhinolaryngology, University Hospital Jena, 07747 Jena, Germany.
J Clin Med. 2024 Oct 3;13(19):5905. doi: 10.3390/jcm13195905.
Paragangliomas represent a surgical challenge due to their hypervascularization. The preoperative selective embolization of these tumors significantly decreases intraoperative blood loss. However, the literature on preoperative embolization in glomus tumors is limited. The aim of this study is to contribute additional evidence regarding the role of preoperative embolization, as well as to evaluate risks and complications in the treatment of glomus tumors. A retrospective evaluation of all the embolizations of glomus tumors from 2009 to 2023 was conducted. The primary outcome parameter was the rate of devascularization after embolization and the occurrence of significant perioperative hemorrhages. The secondary outcome was embolization-related complications. Twenty-one embolizations in 20 patients were investigated in the study. In 43% of the cases more than 90% devascularization was achieved by embolization, while in the remaining cases, 80 to 90% devascularization was reached. In one case (5%), significant perioperative bleeding after embolization occurred. In one case (5%), a symptomatic complication occurred periinterventionally due to the brief dislocation of the coaxial and microcatheter into the internal carotid artery (ICA), which led to fresh punctate DWI lesions on the subsequent MRI. No patients developed nerve palsy following embolization. The preoperative embolization of glomus tumors can lead to significant tumor devascularization and a reduction in perioperative bleeding, with a low complication rate.
副神经节瘤因其血管高度丰富而构成手术挑战。这些肿瘤的术前选择性栓塞可显著减少术中失血。然而,关于球瘤术前栓塞的文献有限。本研究的目的是提供关于术前栓塞作用的更多证据,并评估球瘤治疗中的风险和并发症。对2009年至2023年期间所有球瘤栓塞病例进行了回顾性评估。主要结局参数是栓塞后去血管化率和围手术期严重出血的发生情况。次要结局是栓塞相关并发症。本研究调查了20例患者的21次栓塞。在43%的病例中,栓塞实现了超过90%的去血管化,而在其余病例中,去血管化率达到80%至90%。1例(5%)在栓塞后发生围手术期严重出血。1例(5%)在介入期间出现症状性并发症,原因是同轴导管和微导管短暂移位至颈内动脉(ICA),导致随后的MRI上出现新的点状扩散加权成像(DWI)病变。栓塞后无患者出现神经麻痹。球瘤的术前栓塞可导致显著的肿瘤去血管化并减少围手术期出血,且并发症发生率较低。