Hainan Engineering Research Center of Agarwood, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.
J Asian Nat Prod Res. 2021 Dec;23(12):1156-1163. doi: 10.1080/10286020.2020.1860029. Epub 2020 Dec 18.
Two new 2-(2-phenylethyl)chromone derivatives (-) were isolated from the ethyl acetate extract of artificial agarwood induced by holing method originating from (Lour.) Gilg, and they were isolated from this genus for the first time. The structures of these two new compounds were elucidated by extensive spectroscopic analyses, including UV, IR, one- and two-dimensional NMR and HRESIMS measurements. Bioassay tests of these two new compounds showed compounds and had weak inhibitory activity against acetylcholinesterase at a concentration of 50.0 μg/ml.
从打孔法人工诱导的土沉香（Aquilaria sinensis）（白木香）（Lour.）Gilg 的乙酸乙酯提取物中分离得到两个新的 2-(2-苯乙基)色酮衍生物（-），这是首次从该属中分离得到这些化合物。通过广泛的光谱分析，包括 UV、IR、一维和二维 NMR 和 HRESIMS 测量，确定了这两个新化合物的结构。这两个新化合物的生物测定试验表明，化合物 和 对乙酰胆碱酯酶在 50.0 μg/ml 的浓度下具有较弱的抑制活性。
