Pediatric Intensive Care Unit, Grenoble Alpes University Hospital, Grenoble, France.
Public Health Department, Grenoble Alpes University Hospital, Grenoble, France.
Arch Pediatr. 2021 Feb;28(2):141-146. doi: 10.1016/j.arcped.2020.11.006. Epub 2020 Dec 15.
This study aimed to assess how the emergence of high-flow nasal cannula (HFNC) has modified the demographic and clinical characteristics as well as outcomes of infants with bronchiolitis admitted to a pediatric intensive care unit (PICU).
This was a single-center retrospective study including infants aged 1 day to 6 months with bronchiolitis requiring HFNC, noninvasive ventilation (NIV), or invasive ventilation on admission.
A total of 252 infants (mean age 53±36 days) were included in the study. The use of HFNC increased from 18 (21.4%) during 2013-2014 to 53 infants (55.2%) during 2015-2016. The length of stay in the PICU decreased over time from 4.7±2.9 to 3.5±2.7 days (P<0.01) but the hospital length of stay remained similar (P=0.17). On admission, patients supported by HFNC as the first-line therapy were older. The PICU length of stay was similar according to the type of respiratory support (P=0.16), but the hospital length of stay was longer for patients supported by HFNC (P=0.01).
The distribution of respiratory support has significantly changed over time for patients with bronchiolitis and HFNC is increasingly used. The demographic and clinical characteristics of the have not changed over time. However, the PICU length of stay decreased significantly.
本研究旨在评估高流量鼻导管（HFNC）的出现如何改变了因毛细支气管炎而入住儿科重症监护病房（PICU）的婴儿的人口统计学和临床特征以及结局。
这是一项单中心回顾性研究，纳入了年龄在 1 天至 6 个月之间，因毛细支气管炎需要接受 HFNC、无创通气（NIV）或有创通气的婴儿。
共纳入 252 名婴儿（平均年龄 53±36 天）。HFNC 的使用率从 2013-2014 年的 18 例（21.4%）增加到 2015-2016 年的 53 例（55.2%）。PICU 的住院时间逐渐缩短，从 4.7±2.9 天缩短至 3.5±2.7 天（P<0.01），但住院时间相似（P=0.17）。入院时，接受 HFNC 作为一线治疗的患者年龄更大。根据呼吸支持类型，PICU 住院时间相似（P=0.16），但接受 HFNC 支持的患者的住院时间更长（P=0.01）。
毛细支气管炎患者的呼吸支持分布在时间上发生了显著变化，HFNC 的使用越来越多。患者的人口统计学和临床特征随时间无变化。然而，PICU 的住院时间显著缩短。
