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破裂功能性肾上腺肿瘤,以肾绞痛和高血压为表现的非典型症状。

Ruptured functioning adrenal tumour, atypical presentation with renal colic and hypertension.

机构信息

Emergency Department, Hamad Medical Corporation, Doha, Qatar

Emergency Department, Hamad Medical Corporation, Doha, Qatar.

出版信息

BMJ Case Rep. 2020 Dec 17;13(12):e236050. doi: 10.1136/bcr-2020-236050.

Abstract

Pheochromocytomas are uncommon tumours that originate in chromaffin cells. They are a representation of 0.1%-1% of all cases of secondary hypertension. Most pheochromocytomas are unilateral and benign, featuring catecholamine production, as well as the production of other neuropeptides. Pheochromocytomas are mostly located in the adrenal gland; the frequency of occurrence is highest between 30 and 50 years of age; however, up to 25% of cases may be linked to multiple endocrine neoplasia type 2, Von-Hippel-Landau disease and type 1 neurofibromatosis in the young.We present a case of ruptured left adrenal pheochromocytoma with an atypical presentation. A 30-year-old male patient presented with severe left flank pain and hypertension. The CT scan of the abdomen showed bleeding from the left adrenal mass, where resuscitation and angioembolisation were done. Embolisation of the inferior and superior arteries was done, but the middle failed. The patient experienced a significant drop in haemoglobin and a haemorrhagic shock post angioembolisation, which called for emergency laparotomy. The patient is currently doing well with an uneventful postoperative course.

摘要

嗜铬细胞瘤是起源于嗜铬细胞的罕见肿瘤。它们占继发性高血压所有病例的 0.1%-1%。大多数嗜铬细胞瘤是单侧的良性肿瘤,具有儿茶酚胺的产生以及其他神经肽的产生。嗜铬细胞瘤主要位于肾上腺;其发生频率在 30 至 50 岁之间最高;然而,多达 25%的病例可能与多发性内分泌肿瘤 2 型、Von-Hippel-Landau 病和年轻的 1 型神经纤维瘤病有关。我们报告了一例左侧肾上腺嗜铬细胞瘤破裂的不典型病例。一名 30 岁男性患者因剧烈的左侧腰痛和高血压就诊。腹部 CT 扫描显示左肾上腺肿块出血,进行了复苏和血管栓塞术。进行了下腔和上腔动脉栓塞,但中腔失败。患者在血管栓塞后血红蛋白明显下降并发生出血性休克,需要紧急剖腹手术。目前患者情况良好,术后恢复顺利。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5ed/7747614/2d3aa8ebd95a/bcr-2020-236050f01.jpg

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