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2005 - 2015年乌干达东部城乡结合部及农村地区5岁以下儿童的新生儿后期死亡率

Postneonatal under-5 mortality in peri-urban and rural Eastern Uganda, 2005-2015.

作者信息

Hirose Atsumi, Kajungu Dan, Tusubira Valerie, Waiswa Peter, Alfven Tobias, Hanson Claudia

机构信息

Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden

School of Public Health, Imperial College London, London, UK.

出版信息

BMJ Glob Health. 2020 Dec;5(12). doi: 10.1136/bmjgh-2020-003762.

Abstract

INTRODUCTION

Community and individual sociodemographic characteristics play an important role in child survival. However, a question remains how urbanisation and demographic changes in sub-Saharan Africa affect community-level determinants for child survival.

METHODS

Longitudinal data from the Iganga/Mayuge Health and Demographic Surveillance Site was used to obtain postneonatal under-5 mortality rates between March 2005 and February 2015 in periurban and rural areas separately. Multilevel survival analysis models were used to identify factors associated with mortality.

RESULTS

There were 43 043 postneonatal under-5 children contributing to 116 385 person years of observation, among whom 1737 died. Average annual crude mortality incidence rate (IR) differed significantly between periurban and rural areas (9.0 (8.1 to 10.0) per 1000 person-years vs 18.1 (17.1 to 19.0), respectively). In periurban areas, there was evidence for decreasing mortality from IR=11.3 (7.7 to 16.6) in 2006 to IR=4.5 (3.0 to 6.9) in 2015. The mortality fluctuated with no evidence for reduction in rural areas (IR=19.0 (15.8 to 22.8) in 2006; IR=15.5 (13.0 to 18.6) in 2015). BCG vaccination was associated with reduced mortality in periurban and rural areas (adjusted rate ratio (aRR)=0.45; 95% CI 0.30 to 0.67 and aRR=0.56; 95% CI 0.41 to 0.76, respectively). Maternal education level within the community was associated with reduced mortality in both periurban and rural sites (aRR=0.83; 95% CI 0.70 to 0.99; aRR=0.90; 95% CI 0.81 to 0.99). The proportion of households in the poorest quintile within the community was associated with mortality in rural areas only (aRR=1.08; 95% CI 1.00 to 1.18). In rural areas, a large disparity existed between the least poor and the poorest (aRR=0.50; 95% CI 0.27 to 0.92).

CONCLUSION

We found evidence for a mortality decline in peri-urban but not rural areas. Investments in the known key health (eg, vaccination) and socio-economic interventions (education, and economic development) continue to be crucial for mortality declines. Focused strategies to eliminate the disparity between wealth quintiles are also warranted. There may be equitable access to health services in peri-urban areas but improved metrics of socioeconomic position suitable for peri-urban residents may be needed.

摘要

引言

社区和个人的社会人口特征在儿童生存中起着重要作用。然而,撒哈拉以南非洲的城市化和人口变化如何影响儿童生存的社区层面决定因素仍是一个问题。

方法

使用来自伊甘加/马尤格健康与人口监测点的纵向数据,分别获取2005年3月至2015年2月期间城郊和农村地区5岁以下新生儿后期死亡率。采用多水平生存分析模型来确定与死亡率相关的因素。

结果

共有43043名5岁以下新生儿后期儿童,累计观察人年数达116385人年,其中1737人死亡。城郊和农村地区的年平均粗死亡率发病率(IR)差异显著(分别为每1000人年9.0(8.1至10.0)和18.1(17.1至19.0))。在城郊地区,有证据表明死亡率从2006年的IR = 11.3(7.7至16.6)降至2015年的IR = 4.5(3.0至6.9)。农村地区的死亡率波动,没有下降的证据(2006年IR = 19.0(15.8至22.8);2015年IR = 15.5(13.0至18.6))。卡介苗接种与城郊和农村地区死亡率降低相关(调整率比(aRR)分别为0.45;95%置信区间0.30至0.67和aRR = 0.56;95%置信区间0.41至0.76)。社区内母亲的教育水平与城郊和农村地区死亡率降低相关(aRR = 0.83;95%置信区间0.70至0.99;aRR = 0.90;95%置信区间0.81至0.99)。社区内最贫困五分之一家庭的比例仅与农村地区死亡率相关(aRR = 1.08;95%置信区间1.00至1.18)。在农村地区,最不贫困和最贫困人群之间存在很大差距(aRR = 0.50;95%置信区间0.27至0.92)。

结论

我们发现城郊地区死亡率下降的证据,但农村地区没有。对已知的关键健康(如疫苗接种)和社会经济干预措施(教育和经济发展)的投资对于死亡率下降仍然至关重要。还需要制定有针对性的战略来消除财富五分位数之间的差距。城郊地区可能有公平获得卫生服务的机会,但可能需要改进适合城郊居民的社会经济地位衡量指标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9b2/7747610/1132df64c80d/bmjgh-2020-003762f01.jpg

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