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解决急性肾损伤问题:预防、透析时机和随访。

Tackling AKI: prevention, timing of dialysis and follow-up.

机构信息

Division of Nephrology, Washington University in St. Louis, St. Louis, MO, USA.

出版信息

Nat Rev Nephrol. 2021 Feb;17(2):87-88. doi: 10.1038/s41581-020-00390-3.

DOI:10.1038/s41581-020-00390-3
PMID:33335277
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7745587/
Abstract

Timely diagnosis and dialytic treatment of acute kidney injury (AKI) came to the forefront at the height of the coronavirus disease 2019 pandemic as admissions surged in intensive care units. Research on early diagnosis, timing of initiation of kidney replacement therapy, and appropriate post-hospitalization patient care remains essential to tackling the burden of AKI.

摘要

在 2019 冠状病毒病大流行期间,重症监护病房的入院人数激增,急性肾损伤(AKI)的及时诊断和透析治疗成为关注焦点。关于早期诊断、开始肾脏替代治疗的时机以及适当的住院后患者护理的研究对于应对 AKI 的负担仍然至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8422/7745587/64457aad5125/41581_2020_390_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8422/7745587/64457aad5125/41581_2020_390_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8422/7745587/64457aad5125/41581_2020_390_Fig1_HTML.jpg

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The Relationship between AKI and CKD in Patients with Type 2 Diabetes: An Observational Cohort Study.2 型糖尿病患者急性肾损伤与慢性肾脏病的关系:一项观察性队列研究。
J Am Soc Nephrol. 2021 Jan;32(1):138-150. doi: 10.1681/ASN.2020030323. Epub 2020 Sep 18.
负载氧气的全氟碳纳米颗粒通过改善肾脏氧合水平减轻急性肾损伤。
Biomater Res. 2025 Apr 10;29:0181. doi: 10.34133/bmr.0181. eCollection 2025.
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ESCRT III-mediated lysosomal repair improve renal tubular cell injury in cisplatin-induced AKI.内体分选转运复合体III(ESCRT III)介导的溶酶体修复改善顺铂诱导的急性肾损伤中的肾小管细胞损伤。
Autophagy. 2025 Sep;21(9):1927-1944. doi: 10.1080/15548627.2025.2483598. Epub 2025 Apr 4.
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Urinary exosomes as promising biomarkers for early kidney disease detection.尿外泌体作为早期肾病检测的有前景的生物标志物。
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