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营养不良对桡骨远端骨折手术固定术后30天并发症的影响。

The Impact of Malnutrition on 30-Day Postoperative Complications following Surgical Fixation of Distal Radius Fractures.

作者信息

Newman Jared M, Coste Marine, Dua Karan, Yang Andrew, Cautela Frank S, Shah Neil V, Patel Aakash M, Chee Alexander, Khlopas Anton, Koehler Steven M

机构信息

Department of Orthopaedic Surgery and Rehabilitation Medicine, SUNY Downstate Medical Center, Brooklyn, New York, United States.

Department of Orthopaedic Surgery, Chicago College of Osteopathic Medicine, Midwestern University, Downers Grove, Illinois, United States.

出版信息

J Hand Microsurg. 2020 Oct;12(Suppl 1):S33-S38. doi: 10.1055/s-0039-3400433. Epub 2020 Jan 16.

Abstract

Distal radius fractures (DRFs) are increasingly managed surgically among fragility fractures due to prolonged life expectancy and surgical advancements. Yet, malnutrition can impact postoperative outcomes and complications. We sought to determine the impact of malnutrition on open reduction and internal fixation (ORIF) of DRFs during the perioperative and 30-day postoperative periods.  Using the National Surgical Quality Improvement Program database, all patients who underwent ORIF of a DRF between January 1, 2008, and December 31, 2016, were identified and stratified by preoperative serum albumin levels: normal (≥3.5 g/dL; = 2,546) or hypoalbuminemia (<3.5 g/dL; = 439). Demographical and perioperative data were compared. Operative complications were stratified into major and minor complications, and data were analyzed using descriptive statistics and multivariate regression models.  Compared with patients with normal levels, a higher proportion of hypoalbuminemia patients had ASA scores > 3 (9.1 vs. 2%) and a longer mean length of stay (3.16 vs. 0.83 days). Hypoalbuminemia patients also had 625% greater odds for developing major complications during the 30-day postoperative period (odds ratio = 7.25; 95% confidence interval: 1.91-27.49).  Malnutrition significantly affected outcomes and complications of distal radius ORIF. This study highlights the importance of prevention and treatment of malnutrition in the setting of fragility fractures.

摘要

由于预期寿命延长和手术技术进步,桡骨远端骨折(DRF)在脆性骨折中的手术治疗越来越多。然而,营养不良会影响术后结果和并发症。我们试图确定营养不良在围手术期和术后30天内对桡骨远端骨折切开复位内固定术(ORIF)的影响。

使用国家外科质量改进计划数据库,识别出2008年1月1日至2016年12月31日期间接受桡骨远端骨折切开复位内固定术的所有患者,并根据术前血清白蛋白水平进行分层:正常(≥3.5 g/dL;n = 2546)或低白蛋白血症(<3.5 g/dL;n = 439)。比较人口统计学和围手术期数据。手术并发症分为主要并发症和次要并发症,并使用描述性统计和多变量回归模型进行数据分析。

与白蛋白水平正常的患者相比,低白蛋白血症患者中ASA评分>3的比例更高(9.1%对2%),平均住院时间更长(3.16天对0.83天)。低白蛋白血症患者在术后30天内发生主要并发症的几率也高出625%(优势比=7.25;95%置信区间:1.91 - 27.49)。

营养不良显著影响桡骨远端切开复位内固定术的结果和并发症。本研究强调了在脆性骨折情况下预防和治疗营养不良的重要性。

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