Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China.
National Clinical Research Center for Geriatric Disorders, Beijing, China.
J Alzheimers Dis. 2021;79(2):653-661. doi: 10.3233/JAD-201170.
Education plays a potential important effect on the prevalence and incidence of dementia. However, most of the evidence based on convenience sampling.
To explore effects of education on cognition in individuals with subjective cognitive decline (SCD) and cognitive impairment (CI) from a population-based study.
We examined the effect of education on cognition among individuals with SCD (n = 451) and CI (n = 280) from a population-based study. A series of neuropsychological tests of memory, executive, language, and general cognitive function were used to assess the participants.
Multiple regression analyses revealed that education has a positive effect on cognition in both SCD and CI group in the population-based research. Further stratification study showed that the beneficial effect of education remains in the SCD group regardless of the education level, especially in the SCD participants with a low education level. However, that effect of education exists in the CI group with a low education level and disappears in the high education level.
These results from a population-based sample suggest that high educational attainment may delay cognitive decline in the individuals with SCD regardless of high or low educational level, and high education only predicts cognition in those in the low educational level in CI group.
教育对痴呆的患病率和发病率有潜在的重要影响。然而，大多数基于方便抽样的证据。
从基于人群的研究中探讨教育对主观认知下降（SCD）和认知障碍（CI）个体认知的影响。
我们检查了一项基于人群的研究中 451 名 SCD 患者（n=451）和 280 名 CI 患者（n=280）的教育对认知的影响。使用一系列记忆、执行、语言和一般认知功能的神经心理学测试来评估参与者。
多元回归分析显示，在基于人群的研究中，教育对 SCD 和 CI 组的认知均有积极影响。进一步分层研究表明，无论教育水平如何，教育对 SCD 组的有益影响仍然存在，尤其是在教育程度较低的 SCD 参与者中。然而，在教育程度较低的 CI 组中存在教育的这种影响，而在教育程度较高的 CI 组中则消失。
这些来自基于人群的样本的结果表明，高教育程度可能会延迟 SCD 个体的认知下降，无论其教育程度高低，而高教育程度仅能预测 CI 组中教育程度较低的个体的认知。
