von Lucadou M, Strahm C, Potz S, Toepfer A, Weber M, Passavanti Z, Neumann T
Klinik für Innere Medizin, Kantonsspital St. Gallen, Rorschacherstr. 95, 9007, St. Gallen, Schweiz.
Klinik für Infektiologie, Kantonsspital St. Gallen, St. Gallen, Schweiz.
Internist (Berl). 2021 May;62(5):555-561. doi: 10.1007/s00108-020-00921-x. Epub 2020 Dec 18.
Metastatic fat necrosis due to inflammatory or neoplastic pancreatic diseases is rare. This phenomenon is attributed to systemic effects of pancreatic enzymes. Depending on the sites of fat necrosis, a number of different diseases may be mimicked, leading to incorrect diagnosis and therapies. Many case reports describe the phenomenon of skin, joint and bone manifestations of fat necrosis under the acronym PPP (pancreatic, panniculits, polyarthritis) syndrome. The management of "autodigestion" primarily consists of treating the underlying pancreatic disease.
由炎症性或肿瘤性胰腺疾病引起的转移性脂肪坏死较为罕见。这种现象归因于胰腺酶的全身作用。根据脂肪坏死的部位,可能会模仿多种不同的疾病,从而导致诊断和治疗错误。许多病例报告以PPP(胰腺、脂膜炎、多关节炎)综合征的首字母缩写描述了脂肪坏死的皮肤、关节和骨骼表现现象。“自身消化”的处理主要包括治疗潜在的胰腺疾病。