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肌肉图谱探索者:一个研究人类骨骼肌基因表达的网络服务。

MuscleAtlasExplorer: a web service for studying gene expression in human skeletal muscle.

机构信息

Genomics, Diabetes and Endocrinology Unit, Department of Clinical Sciences, Lund University Diabetes Centre, Jan Waldenströms gata 35, Malmö 20502, Sweden.

SciLifeLab, BMC, Husargatan 3, Uppsala University, Uppsala 751 22, Sweden.

出版信息

Database (Oxford). 2020 Dec 18;2020. doi: 10.1093/database/baaa111.

Abstract

MuscleAtlasExplorer is a freely available web application that allows for the exploration of gene expression data from human skeletal muscle. It draws from an extensive publicly available dataset of 1654 skeletal muscle expression microarray samples. Detailed, manually curated, patient phenotype data, with information such as age, sex, BMI and disease status, are combined with skeletal muscle gene expression to provide insights into gene function in skeletal muscle. It aims to facilitate easy exploration of the data using powerful data visualization functions, while allowing for sample selection, in-depth inspection and further analysis using external tools. Availability: MuscleAtlasExplorer is available at https://mae.crc.med.lu.se/mae2 (username 'muscle' and password 'explorer' pre-publication).

摘要

肌肉图谱探索者是一个免费的网络应用程序,允许探索人类骨骼肌的基因表达数据。它来源于一个包含 1654 个骨骼肌表达微阵列样本的广泛公开数据集。详细的、经过精心整理的、患者表型数据,包含年龄、性别、BMI 和疾病状态等信息,与骨骼肌基因表达相结合,提供了对骨骼肌中基因功能的深入了解。它旨在通过强大的数据可视化功能方便地探索数据,同时允许使用外部工具进行样本选择、深入检查和进一步分析。可访问性:肌肉图谱探索者可在 https://mae.crc.med.lu.se/mae2 获得(发布前用户名是“muscle”,密码是“explorer”)。

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