Zhang David L, Shapiro Michael J, Schechet Sidney A, Rabiah Peter K, Rodriguez Sarah H, Blair Michael P
Ophthalmic Surg Lasers Imaging Retina. 2020 Dec 1;51(12):698-705. doi: 10.3928/23258160-20201202-04.
To report a series of exudative retinal detachments (ERDs) following laser photocoagulation for retinopathy of prematurity (ROP).
Retrospective case series.
Eleven eyes of seven infants were identified who developed ERD following laser. Median gestation age was 25 weeks (interquartile range [IQR]: 24-27 weeks), and median birth weight was 662 grams (IQR: 538-850 grams). Median postmenstrual age at time of laser was 35 weeks (IQR: 33-39 weeks). ERD was diagnosed at a median of 7 days (IQR: 5-7 days) after laser and was managed with steroids. Bevacizumab was also used for certain cases. Time to resolution ranged from 1 to 5 weeks. Macular pigment changes, atrophy, window defect on fluorescein angiography, and photoreceptor loss on optical coherence tomography were noted in some cases following ERD resolution. Excluding one patient who expired at 3 months, median length of follow-up was 10 years (IQR: 9-13.5 years). Overall, only one patient, who presented with less severe ERD, had normal vision.
ERD is an uncommonly reported complication following laser for ROP. Macular changes following ERD resolution may have negative visual consequences. [Ophthalmic Surg Lasers Imaging Retina. 2020;51:698-705.].
报告一系列早产儿视网膜病变（ROP）激光光凝术后发生的渗出性视网膜脱离（ERD）。
回顾性病例系列研究。
确定7例婴儿的11只眼睛在激光治疗后发生了ERD。中位胎龄为25周（四分位间距[IQR]：24 - 27周），中位出生体重为662克（IQR：538 - 850克）。激光治疗时的中位孕龄为35周（IQR：33 - 39周）。ERD在激光治疗后中位7天（IQR：5 - 7天）被诊断出来，并采用类固醇进行治疗。某些病例也使用了贝伐单抗。消退时间为1至5周。在ERD消退后的一些病例中，观察到黄斑色素改变、萎缩、荧光素血管造影上的窗样缺损以及光学相干断层扫描上的光感受器丢失。除1例在3个月时死亡的患者外，中位随访时间为10年（IQR：9 - 13.5年）。总体而言，只有1例ERD较轻的患者视力正常。
ERD是ROP激光治疗后一种较少报道的并发症。ERD消退后的黄斑改变可能会对视力产生不良影响。[《眼科手术、激光与视网膜成像》。2020；51：698 - 705。]
