Ghantous Yasmin, Nashef Aysar, Mohanna Aladdin, Abu-El-Naaj Imad
Department of Oral and Maxillofacial Surgery, Baruch Padeh Medical Center Poriya, Tiberias 158001, Israel.
The Azrieli Faculty of Medicine, Bar Illan University, 8 Henrietta Szold St, Safed 1310000, Israel.
Nanomaterials (Basel). 2020 Dec 16;10(12):2523. doi: 10.3390/nano10122523.
Defects in the oral and maxillofacial (OMF) complex may lead to functional and esthetic impairment, aspiration, speech difficulty, and reduced quality of life. Reconstruction of such defects is considered one of the most challenging procedures in head and neck surgery. Transfer of different auto-grafts is still considered as the "gold standard" of regenerative and reconstructive procedures for OMF defects. However, harvesting of these grafts can lead to many complications including donor-site morbidity, extending of surgical time, incomplete healing of the donor site and others. Three-dimensional (3D) printing technology is an innovative technique that allows the fabrication of personalized implants and scaffolds that fit the precise anatomy of an individual's defect and, therefore, has attracted significant attention during the last few decades, especially among head and neck surgeons. Here we discuss the most relevant applications of the 3D printing technology in the oral and maxillofacial surgery field. We further show different clinical examples of patients who were treated at our institute using the 3D technology and discuss the indications, different technologies, complications, and their clinical outcomes. We demonstrate that 3D technology may provide a powerful tool used for reconstruction of various OMF defects, enabling optimal clinical results in the suitable cases.
口腔颌面(OMF)复合体的缺损可能导致功能和美观受损、误吸、言语困难以及生活质量下降。此类缺损的重建被认为是头颈外科中最具挑战性的手术之一。不同自体移植物的转移仍被视为OMF缺损再生和重建手术的“金标准”。然而,获取这些移植物会导致许多并发症,包括供区并发症、手术时间延长、供区愈合不完全等。三维(3D)打印技术是一种创新技术,能够制造适合个体缺损精确解剖结构的个性化植入物和支架,因此在过去几十年中受到了广泛关注,尤其是在头颈外科医生中。在此,我们讨论3D打印技术在口腔颌面外科领域的最相关应用。我们还展示了在我们研究所接受3D技术治疗的患者的不同临床案例,并讨论了适应症、不同技术、并发症及其临床结果。我们证明,3D技术可为各种OMF缺损的重建提供有力工具,在合适的病例中实现最佳临床效果。