Takayama Izumi, Katayama Akito, Terakawa Mitsuhiro
School of Integrated Design Engineering, Keio University, 3-14-1, Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
Department of Electronics and Electrical Engineering, Keio University, 3-14-1, Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
Nanomaterials (Basel). 2020 Dec 16;10(12):2529. doi: 10.3390/nano10122529.
The fabrication of hollow channels surrounded by gold nanoparticles in poly(ethylene glycol) diacrylate (PEGDA) is demonstrated. The absorption spectra show that gold nanoparticles were formed at the periphery of the focus by reduction of gold ions. The microscope observation and Raman spectroscopy analyses indicate that the center of the channels were void of PEGDA, which can be attributed to the femtosecond laser-induced degradation of the hydrogel. Since both the hydrogel and gold nanoparticles are biocompatible, this technique of fabricating hollow channels surrounded by gold nanoparticles is promising for tissue engineering, drug screening, and lab-on-a-chip devices.
展示了在聚（乙二醇）二丙烯酸酯（PEGDA）中制备被金纳米颗粒包围的中空通道。吸收光谱表明，通过金离子的还原，在焦点周围形成了金纳米颗粒。显微镜观察和拉曼光谱分析表明，通道中心没有PEGDA，这可归因于飞秒激光诱导的水凝胶降解。由于水凝胶和金纳米颗粒都具有生物相容性，这种制备被金纳米颗粒包围的中空通道的技术在组织工程、药物筛选和芯片实验室设备方面具有广阔前景。
