FinnHEMS Research and Development Unit, Vantaa, Finland.
University of Helsinki, Helsinki, Finland.
Acta Anaesthesiol Scand. 2021 Jul;65(6):816-823. doi: 10.1111/aas.13765. Epub 2021 Mar 20.
The value of shock-index has been demonstrated in hospital triage, but few studies have evaluated its prehospital use. The aim of our study was to evaluate the association between shock-index in prehospital critical care and short-term mortality.
We analyzed data from the national helicopter emergency medical services database and the Population Register Centre. The shock-index was calculated from the patients' first measured parameters. The primary outcome measure was 1- and 30-day mortality.
A total of 22 433 patients were included. The 1-day mortality was 7.5% and 30-day mortality was 16%. The median shock-index was 0.68 (0.55/0.84) for survivors and 0.67 (0.49/0.93) for non-survivors (P = .316) at 30-days. Association between shock-index and mortality followed a U-shaped curve in trauma (shock-index < 0.5: odds ratio 2.5 [95% confidence interval 1.8-3.4], shock-index > 1.3: odds ratio 4.4 [2.7-7.2] at 30 days). Patients with neurological emergencies with a low shock-index had an increased risk of mortality (shock-index < 0.5: odds ratio 1.8 [1.5-2.3]) whereas patients treated after successful resuscitation from out-of-hospital cardiac arrest, a higher shock-index was associated with higher mortality (shock-index > 1.3: odds ratio 3.5 [2.3-5.4). The association was similar for all ages, but older patients had higher mortality in each shock-index category.
The shock-index is associated with short time mortality in most critical patient categories in the prehospital setting. However, the marked overlap of shock-index in survivors and non-survivors in all patient categories limits its predictive value.
休克指数在医院分诊中具有重要价值,但很少有研究评估其院前应用。本研究旨在评估院前急救中休克指数与短期死亡率之间的关联。
我们分析了国家直升机紧急医疗服务数据库和人口登记中心的数据。休克指数根据患者的首次测量参数计算。主要结局指标为 1 天和 30 天死亡率。
共纳入 22433 例患者。1 天死亡率为 7.5%,30 天死亡率为 16%。幸存者的休克指数中位数为 0.68(0.55/0.84),非幸存者为 0.67(0.49/0.93)(P=0.316)。在创伤患者中,休克指数与死亡率之间呈 U 型曲线相关(休克指数<0.5:比值比 2.5[95%置信区间 1.8-3.4],休克指数>1.3:比值比 4.4[2.7-7.2],30 天)。患有神经急症且休克指数较低的患者死亡风险增加(休克指数<0.5:比值比 1.8[1.5-2.3]),而从院外心脏骤停复苏成功后接受治疗的患者,休克指数较高与更高的死亡率相关(休克指数>1.3:比值比 3.5[2.3-5.4])。这种关联在所有年龄段都是相似的,但在每个休克指数类别中,老年患者的死亡率更高。
在院前环境中,休克指数与大多数危急患者类别的短期死亡率相关。然而,在所有患者类别中,幸存者和非幸存者的休克指数存在明显重叠,限制了其预测价值。