Southern Synergy, Monash University, Melbourne, Australia.
University Centre for Rural Health, University of Sydney, Lismore, Australia.
Early Interv Psychiatry. 2021 Oct;15(5):1326-1334. doi: 10.1111/eip.13085. Epub 2020 Dec 19.
The purpose of this pilot study was to determine the feasibility, acceptability and the potential clinical utility of a novel mindfulness and compassion program (MAC-P) designed for youth with a range of psychotic experiences.
A non-randomised, non-controlled prospective follow-up study was conducted. Eighteen participants who either met criteria for the 'at risk mental state' or were experiencing a psychotic episode or had a recent diagnosis of schizophrenia attended the 8-week program. Participants completed clinical assessments pre-treatment, post-treatment and at 6-week follow-up which measured a range of symptoms (psychosis, anxiety, depression and stress) and psychosocial outcomes.
Attendance and retention data indicated that MAC-P is a feasible and acceptable program. There was a large significant increase in self-compassion. Mindfulness demonstrated a positive change over time. There was a large significant effect on one subscale-acting with awareness. There were significant reductions in distress associated with psychotic experiences as well as anxiety, depression, stress and self-criticism. Significant improvements in functioning and insecure attachment styles were also found. Regression results demonstrated that self-compassion was associated with a number of these findings.
The MAC-P for youth shows potential as a clinically effective intervention provided as an addition to treatment as usual for youth with psychotic experiences. A larger controlled study is needed to validate the effectiveness of this intervention.
本试点研究旨在确定一种针对不同精神病经历的青年设计的新型正念和同情心计划（MAC-P）的可行性、可接受性和潜在临床效用。
进行了一项非随机、非对照的前瞻性随访研究。18 名符合“高危心理状态”标准或正在经历精神病发作或最近被诊断为精神分裂症的参与者参加了为期 8 周的计划。参与者在治疗前、治疗后和 6 周随访时完成了一系列症状（精神病、焦虑、抑郁和压力）和心理社会结果的临床评估。
出席和保留数据表明，MAC-P 是一个可行和可接受的计划。自我同情有了很大的显著增加。正念随着时间的推移表现出积极的变化。在一个子量表-带着意识行动上有很大的显著效果。与精神病经历相关的痛苦以及焦虑、抑郁、压力和自我批评都有显著减少。功能和不安全依恋模式也有显著改善。回归结果表明，自我同情与这些发现中的许多发现有关。
针对青年的 MAC-P 显示出作为一种有前途的临床有效干预措施，可作为精神病经历青年的常规治疗的补充。需要进行更大规模的对照研究来验证这种干预措施的有效性。
