Department of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Glasgow Mental Health Research Facility, University of Glasgow, Glasgow, UK.
Br J Clin Psychol. 2023 Nov;62(4):762-781. doi: 10.1111/bjc.12437. Epub 2023 Aug 27.
Compassion-focused therapy (CFT) is an evolution-informed biopsychosocial approach that seeks to cultivate attachment and care motivational systems and their psychophysiological regulators. These can counteract some of the harmful effects of social threat, inferiority, shame, self-criticism and depression, which are common in people with psychosis and undermine their well-being, social trust and ability to feel safe. This study aimed to test the acceptability of a novel manualized individual CFT intervention for psychosis (CFTp).
A non-concurrent, multiple-baseline, case series design, with three phases: baseline, intervention and follow-up.
The 26-session CFTp intervention was provided for a sample of eight people with distressing psychotic experiences and a psychosis-related diagnosis. The study aimed to assess acceptability of CFTp and to test clinically reliable improvements while receiving the intervention, compared to a baseline period.
Seven of eight participants completed the therapy, and clinically reliable improvements were found at both the single-case and group level of analysis. At the single-case level, over half the participants showed improvements in depression (5/7), stress (5/7), distress (5/7), anxiety (4/7) and voices (3/5). One participant showed a deterioration in anxiety (1/7) and dissociation (1/7). At the group level (n = 7), there were significant improvements in depression, stress, distress, voices and delusions. The improvements in voices, delusions and distress were sustained at 6- to 8-week follow-up, but depression and stress dropped slightly to trend-level improvements.
CFTp is a feasible and acceptable intervention for psychosis, and further investigation is warranted with a randomized controlled trial.
关注共情的疗法（CFT）是一种进化启发的生物心理社会方法，旨在培养依恋和关怀动机系统及其心理生理学调节因素。这些可以抵消社交威胁、自卑感、羞耻感、自我批判和抑郁在精神病患者中常见的一些有害影响，这些因素会破坏他们的幸福感、社会信任和安全感。本研究旨在测试一种针对精神病的新型个体化关注共情疗法（CFTp）的可接受性。
采用非同期、多基线、病例系列设计，分为三个阶段：基线期、干预期和随访期。
对 8 名有痛苦的精神病体验和与精神病相关的诊断的参与者进行了 26 节 CFTp 干预。该研究旨在评估 CFTp 的可接受性，并在接受干预时测试临床可靠的改善情况，与基线期相比。
8 名参与者中有 7 名完成了治疗，在单病例和组水平的分析中均发现了临床可靠的改善。在单病例水平上，超过一半的参与者在抑郁（5/7）、压力（5/7）、痛苦（5/7）、焦虑（4/7）和幻听（3/5）方面有所改善。一名参与者在焦虑（1/7）和分离（1/7）方面出现恶化。在组水平（n=7），抑郁、压力、痛苦、幻听和妄想均有显著改善。幻听、妄想和痛苦的改善在 6-8 周随访时持续，但抑郁和压力略有下降至趋势改善水平。
CFTp 是一种针对精神病的可行且可接受的干预措施，需要进一步进行随机对照试验的研究。
