Department of Physical Therapy, Faculty of Health and Welfare, Tokushima Bunri University, Tokushima, Japan.
Department of Physical Therapy, Faculty of Health, Medical care, and Welfare, Kibi International University, Takahashi, Okayama, Japan.
J Stroke Cerebrovasc Dis. 2021 Mar;30(3):105543. doi: 10.1016/j.jstrokecerebrovasdis.2020.105543. Epub 2020 Dec 17.
The aim of the current study was to examine longitudinal changes in quadriceps muscle mass and intramuscular adipose tissue in chronic stroke survivors.
In this longitudinal study included 34 chronic stroke survivors who lived in the community. Ultimately, 20 chronic stroke survivors received an after 3-year assessment. Fourteen chronic stroke survivors were lost at follow-up. Chronic stroke survivors who were followed and not followed during 3 years were categorized as follow-up group and lost follow-up group, respectively. The quadriceps muscle mass and intramuscular adipose tissue were assessed at baseline and after 3-year assessments based on muscle thickness and echo intensity in ultrasound images, respectively.
No significant differences in any characteristics were observed between the flow-up and lost follow-up groups. In the follow-up group, there was a significant decrease in quadriceps thickness on the paretic (10.3% decrease) and non-paretic (17.0% decrease) sides at follow-up after 3 years compared with baseline. There was a significant increase in quadriceps echo intensity on the paretic (20.0% increase) and non-paretic (24.9% increase) sides at follow-up after 3 years compared with baseline. There were significant positive relationships between changes in body weight and changes in quadriceps thickness on the paretic and non-paretic sides. Chronic stroke survivors with greater reductions in body weight showed a trend towards a greater decrease in quadriceps thickness on the paretic and non-paretic sides.
The current results suggest marked longitudinal changes in the skeletal muscles in chronic stroke survivors. Preventing secondary changes in skeletal muscles and limiting decreases in body weight are essential for improving outcomes in chronic stroke survivors.
本研究旨在探讨慢性脑卒中幸存者股四头肌质量和肌内脂肪组织的纵向变化。
本纵向研究纳入了 34 名居住在社区的慢性脑卒中幸存者。最终，20 名慢性脑卒中幸存者接受了 3 年后的评估。14 名慢性脑卒中幸存者在随访中失访。随访 3 年的慢性脑卒中幸存者和未随访的慢性脑卒中幸存者分别归类为随访组和失访组。股四头肌质量和肌内脂肪组织分别根据超声图像中的肌肉厚度和回声强度在基线和 3 年后评估。
随访组和失访组在任何特征方面均无显著差异。在随访组中，与基线相比，3 年后随访时患侧（10.3%减少）和非患侧（17.0%减少）股四头肌厚度显著减少。与基线相比，3 年后随访时患侧（20.0%增加）和非患侧（24.9%增加）股四头肌回声强度显著增加。体重变化与患侧和非患侧股四头肌厚度变化之间存在显著的正相关关系。体重减轻较多的慢性脑卒中幸存者，其患侧和非患侧股四头肌厚度减少的趋势更大。
目前的结果表明，慢性脑卒中幸存者的骨骼肌发生了明显的纵向变化。预防骨骼肌的继发性变化和限制体重下降对于改善慢性脑卒中幸存者的预后至关重要。
