Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Department of Health Science, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Clin Interv Aging. 2022 Dec 15;17:1851-1861. doi: 10.2147/CIA.S385469. eCollection 2022.
Muscle mass, a key index for the diagnosis of sarcopenia, is currently assessed using the appendicular skeletal muscle mass index (ASMI) by bioelectrical impedance analysis (BIA). Muscle thickness (MT) assessed by ultrasonography (US) may be a better determinant and/or predictor of muscle condition than ASMI. Thus, we compared it to the ASMI determined by the BIA.
Our study included 165 ambulatory older adults (84 males, 81 females, mean age: 76.82 years). The ASMI by the BIA method, MT by US, and the distribution of body mass index (BMI) and body fat percentage (BFP) were examined using defined values for men and women. These were used as the basis for examining the association of MT and ASMI with handgrip strength (HGS), leg muscle strength (LMS), gait speed (GS), and echo intensity (EI). We compared HGS, LMS, GS, and EI for high and low ASMI among lower BMI or BFP. The same was also done for MT assessed by US.
MT, as well as ASMI, was strongly associated with HGS and LMS. There was a correlation between MT and GS and EI but not between ASMI and GS and EI. There were significant differences in the prevalence between high ASMI and high MT or low ASMI and low MT in those with lower BMI or BFP. In non-overweight participants, HGS, LMS, GS, and EI were significantly higher in those with high MT than in those with low MT; however, there were no significant differences in them between those with high and low ASMI.
In the non-overweight group, the MT assessment by US showed a stronger relationship to muscle strength and muscle quality than the ASMI assessment by BIA. The MT assessment using US is a useful alternative to BIA-assessed ASMI, especially in non-overweight participants.
骨骼肌质量是肌少症诊断的关键指标，目前通过生物电阻抗分析（BIA）评估四肢骨骼肌质量指数（ASMI）。超声（US）评估的肌肉厚度（MT）可能比 ASMI 更能确定和/或预测肌肉状况。因此，我们将其与 BIA 确定的 ASMI 进行了比较。
本研究纳入了 165 名有活动能力的老年人（84 名男性，81 名女性，平均年龄：76.82 岁）。使用男女定义值检查 BIA 法的 ASMI、US 的 MT 以及体重指数（BMI）和体脂百分比（BFP）的分布。这些值被用作检查 MT 和 ASMI 与握力（HGS）、腿部肌肉力量（LMS）、步态速度（GS）和回声强度（EI）之间关联的基础。我们比较了低 BMI 或 BFP 中高和低 ASMI 人群的 HGS、LMS、GS 和 EI。US 评估的 MT 也进行了相同的比较。
MT 和 ASMI 与 HGS 和 LMS 均密切相关。MT 与 GS 和 EI 之间存在相关性，但 ASMI 与 GS 和 EI 之间无相关性。在 BMI 或 BFP 较低的人群中，高 ASMI 和高 MT 或低 ASMI 和低 MT 之间的患病率存在显著差异。在非超重参与者中，高 MT 组的 HGS、LMS、GS 和 EI 明显高于低 MT 组；然而，高 ASMI 和低 ASMI 组之间没有显著差异。
在非超重组中，US 评估的 MT 与肌肉力量和肌肉质量的关系比 BIA 评估的 ASMI 更强。US 评估的 MT 是 BIA 评估的 ASMI 的有用替代方法，尤其是在非超重参与者中。
