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感染:一项单中心4年描述性分析。

Infection: A Single-center 4-year Descriptive Analysis.

作者信息

Albarillo Fritzie S, Shah Ushma, Joyce Cara, Slade David

机构信息

Division of Infectious Diseases, Loyola University Medical Center, Maywood, USA.

Northwest Infectious Disease Consultants, Niles, IL 60714, USA.

出版信息

J Glob Infect Dis. 2020 Aug 29;12(3):119-123. doi: 10.4103/jgid.jgid_112_19. eCollection 2020 Jul-Sep.

DOI:10.4103/jgid.jgid_112_19
PMID:33343161
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7733428/
Abstract

INTRODUCTION

is an anaerobic or facultative anaerobic Gram-positive rod that is commonly found in the human gastrointestinal tract and vaginal tract. Infections secondary to have not been well illustrated in the literature. The purpose of this study was to describe the clinical courses of patients with infection in our institution.

MATERIALS AND METHODS

A retrospective chart review was performed on patients with the growth of or from January 1, 2013, to December 31, 2017.

RESULTS

Forty-seven patients had growth of or . Of these, 35 patients were included in the study who received therapy. Twenty patients (57.1%) presented with leukocytosis, 17 (48.5%) with fever, and 15 (42.8%) with abdominal pain. Twenty-three (66.1%) had intra-abdominal infection, 8 (22.3%) were bacteremic, and 4 (11.4%) had mediastinitis. Thirty-three patients (94.3%) had a polymicrobial infection. Eighteen (51.4%) patients had disruption of the gastrointestinal tract, 14 (40.0%) had underlying malignancy, and 11 (31.4%) had prior antibiotic exposure. Twenty (57.1%) patients clinically improved after therapy. However, the overall mortality rate was 56.2%, all of whom died of unrelated causes.

CONCLUSION

are organisms thought to have low pathogenicity. Our study identified cases of infections in a population of patients with serious underlying medical conditions.

摘要

引言

是一种厌氧或兼性厌氧的革兰氏阳性杆菌,常见于人类胃肠道和阴道。继发于感染的情况在文献中尚未得到充分阐述。本研究的目的是描述我院感染患者的临床病程。

材料与方法

对2013年1月1日至2017年12月31日期间培养出或的患者进行回顾性病历审查。

结果

47例患者培养出或。其中,35例接受治疗的患者被纳入研究。20例(57.1%)出现白细胞增多,17例(48.5%)发热,15例(42.8%)腹痛。23例(66.1%)发生腹腔内感染,8例(22.3%)发生菌血症,4例(11.4%)发生纵隔炎。33例患者(94.3%)为混合菌感染。18例(51.4%)患者出现胃肠道破裂,14例(40.0%)有潜在恶性肿瘤,11例(31.4%)曾接受过抗生素治疗。20例(57.1%)患者治疗后临床症状改善。然而,总体死亡率为56.2%,所有患者均死于无关原因。

结论

被认为是致病性较低的微生物。我们的研究在患有严重基础疾病的患者群体中发现了感染病例。

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