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新冠疫情对三级医疗急诊科心房颤动发病率及电复律的影响:跨年度及年度内分析

The Impact of the COVID-19 Pandemic on Incidences of Atrial Fibrillation and Electrical Cardioversion at a Tertiary Care Emergency Department: An Inter- and Intra-year Analysis.

作者信息

Schnaubelt Sebastian, Domanovits Hans, Niederdoeckl Jan, Schuetz Nikola, Cacioppo Filippo, Oppenauer Julia, Spiel Alexander O, Laggner Anton N

机构信息

Department of Emergency Medicine, Medical University of Vienna, Vienna, Austria.

Vienna Health Care Group, Department of Emergency Medicine, Clinic Ottakring, Vienna, Austria.

出版信息

Front Med (Lausanne). 2020 Dec 4;7:595881. doi: 10.3389/fmed.2020.595881. eCollection 2020.

Abstract

National authorities have introduced measures as lockdowns against spreading of COVID-19 and documented incidences of multiple non-COVID-19 diseases have dropped. Yet, data on workload dynamics concerning atrial fibrillation and electrical cardioversion whilst a national lockdown are scarce and may assist in future planning. Documented cases of atrial fibrillation and respective electrical cardioversion episodes at the Emergency Department of the Medical University of Vienna, Austria, from 01/01/2020 to 31/05/2020 were assessed. As reference groups, those incidences were calculated for the years 2017, 2018, and 2019. Inter- and intra-year analyses were conducted through Chi-square test and Poisson regression. A total of 2,310 atrial fibrillation-, and 511 electrical cardioversion episodes were included. We found no significant incidence differences in inter-year analyses of the time periods from January to May, or of the weeks pre- and post the national lockdown due to the COVID-19 pandemic. However, the intra-year analysis of the year 2020 showed a trend toward decreased atrial fibrillation incidences (rate-ratio 0.982, CI 0.964-1.001, = 0.060), and significantly increased electrical cardioversion incidences in the post-lockdown period (rate ratio 1.051, CI 1.008-10.96, = 0.020). The decreased atrial fibrillation incidences are in line with international data. However, an increased demand of electrical cardioversions during the lockdown period was observed. A higher threshold to seek medical attention may produce a selected group with potentially more severe clinical courses. In addition, lifestyle modifications during isolation and a higher stress level may promote atrial fibrillation episodes to be refractory to other therapeutic approaches than electrical cardioversion.

摘要

各国政府已采取措施,如实施封锁以防止新冠病毒传播,多种非新冠疾病的确诊发病率有所下降。然而,关于全国封锁期间心房颤动和电复律工作量动态的数据却很稀少,而这些数据可能有助于未来的规划。我们评估了2020年1月1日至2020年5月31日期间奥地利维也纳医科大学急诊科记录的心房颤动病例及相应的电复律事件。作为参考组,计算了2017年、2018年和2019年的发病率。通过卡方检验和泊松回归进行年度间和年度内分析。共纳入2310例心房颤动病例和511次电复律事件。我们发现,在对1月至5月期间、以及因新冠疫情实施全国封锁前后几周进行的年度间分析中,发病率没有显著差异。然而,2020年的年度内分析显示,心房颤动发病率有下降趋势(率比0.982,置信区间0.964 - 1.001,P = 0.060),而在封锁期后的电复律发病率显著增加(率比1.051,置信区间1.008 - 1.09

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38e0/7746864/d204f755eb80/fmed-07-595881-g0001.jpg

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