Dipartimento Ambiente e Salute, Istituto Superiore di Sanità, Rome, Italy.
Direzione Generale della Sanità Animale e dei Farmaci Veterinari, Ministero della Salute, Rome, Italy.
Ann Ist Super Sanita. 2020 Oct-Dec;56(4):492-496. doi: 10.4415/ANN_20_04_12.
It is worldwide recognized that the use of pharmaceuticals for human and veterinary purposes could lead to unsustainable effects on the environment. A strategy to reduce the impact of pharmaceuticals on the environment has been recently established at European level, where guidelines to evaluate the impacts of veterinary drugs used to treat animal diseases are in place. The aim of this article is to focus on the worldwide used antiparasitic drug ivermectin (IVM) and its potential impact on the environment. A specific section is related to the IVM resistance that the massive use of this drug could generate enhancing the risk scenarios also for human health. The application of stringent measures for the veterinary use of this substance, in line with the recommendations provided by International frameworks such as One Health and EcoHealth, is recommended.
人们普遍认识到，人类和兽医用途的药品的使用可能会对环境造成不可持续的影响。最近在欧洲层面上制定了一项减少药品对环境影响的战略，其中制定了评估用于治疗动物疾病的兽药影响的准则。本文的目的是关注在世界范围内使用的抗寄生虫药物伊维菌素（IVM）及其对环境的潜在影响。专门有一节涉及到这种药物的大规模使用可能产生的 IVM 耐药性，这也增加了对人类健康的风险情景。建议对这种物质的兽医使用采取严格的措施，符合“同一健康”和“生态健康”等国际框架所提供的建议。
