Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Key Laboratory of Materials for Energy Conversion and Storage of Shanxi Province, Institute of Molecular Science, Shanxi University, Taiyuan 030006, China.
Research Institute of Applied Chemistry, Shanxi University, Taiyuan 030006, China.
Chem Commun (Camb). 2021 Jan 21;57(5):655-658. doi: 10.1039/d0cc07398a.
Based on the change in electron distribution of the benzopyrylium unit before and after sulfite addition, a 2-(2'-hydroxyphenyl)benzothiazole (HBT)-based fluorophore generated the excited state intramolecular proton transfer (ESIPT) process with a near-infrared enhanced emission at 836 nm and a large Stokes shift (286 nm). The probe was applied to image SO2 derivatives in cells and mice. Our data will provide new ideas for the development of ESIPT-based fluorescence probe with longer wavelength emission.
基于亚硫酸盐添加前后苯并吡喃单元的电子分布变化，基于 2-(2'-羟基苯基)苯并噻唑 (HBT) 的荧光团产生了具有近红外增强发射的激发态分子内质子转移 (ESIPT) 过程，发射波长为 836nm，Stokes 位移较大（286nm）。该探针被用于细胞和小鼠中 SO2 衍生物的成像。我们的数据将为开发具有更长波长发射的基于 ESIPT 的荧光探针提供新的思路。
