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"True" 全髋关节置换术后 2 年内因骨关节炎导致髋关节脱位的累积发生率和危险因素:来自丹麦髋关节置换登记处的全国基于人群的研究。

"True" Cumulative Incidence of and Risk Factors for Hip Dislocation within 2 Years After Primary Total Hip Arthroplasty Due to Osteoarthritis: A Nationwide Population-Based Study from the Danish Hip Arthroplasty Register.

机构信息

Department of Orthopaedics, Hospital of South West Jutland, Esbjerg, Denmark.

Orthopaedic Research Unit, Department of Orthopaedic Surgery and Traumatology, Odense University Hospital, Odense, Denmark.

出版信息

J Bone Joint Surg Am. 2021 Feb 17;103(4):295-302. doi: 10.2106/JBJS.19.01352.

Abstract

BACKGROUND

Hip dislocation is one of the leading indications for revision of total hip arthroplasty (THA) implants, and the extent of this complication is often measured by the number of revisions. The exact incidence of dislocation can be difficult to establish as closed reductions may not be captured in available registers. The purpose of this study was to identify the "true" cumulative incidence of hip dislocation (revisions and closed reductions) after primary THA, and the secondary aim was to identify risk factors for dislocation.

METHODS

From the Danish Hip Arthroplasty Register, we identified 31,105 primary THAs indicated by primary osteoarthritis that had been performed from 2010 to 2014 and had 2 years of follow-up. Dislocations were identified through extraction from the Danish National Patient Register. Matching diagnosis and procedure codes were deemed correct while non-matching codes were reviewed through a comprehensive, nationwide review of patient files. Risk factors were analyzed with multiple logistic regression analysis and presented as odds ratios (ORs) with 95% confidence intervals (CIs).

RESULTS

Our review of patient files identified 1,861 dislocations in 1,079 THAs, which corresponds to a 2-year cumulative incidence of 3.5% (CI = 3.3% to 3.7%). This was a 50% increase compared with the correctly coded dislocations captured by administrative register data only. Patients who were <65 years of age had a lower dislocation risk (OR = 0.70; CI = 0.59 to 0.83) and those who were >75 years of age had a higher risk (OR = 1.32; CI = 1.14 to 1.52) compared with those who were 65 to 75. Male sex (OR = 0.86; CI = 0.75 to 0.98), cemented fixation (OR = 0.71; CI = 0.58 to 0.87), and lateral approach (OR = 0.28; CI = 0.16 to 0.49) were all associated with a lower risk. A head size of 32 mm was associated with a higher risk of dislocation (OR = 1.27; CI = 1.10 to 1.46) than 36-mm heads, whereas dual-mobility cups had a reduced risk (OR = 0.13; CI = 0.05 to 0.36).

CONCLUSIONS

We found the "true" cumulative incidence of dislocations within 2 years after primary THAs performed between 2010 and 2014 in Denmark to be 3.5%. Age, sex, American Society of Anesthesiologists (ASA) score, head size and type, fixation method, and surgical approach were independent significant factors for dislocation. Comprehensive search algorithms are needed in order to identify all dislocations so that this complication can be accurately reported in national registers.

摘要

背景

髋关节脱位是全髋关节置换术(THA)翻修的主要指征之一,这种并发症的程度通常通过翻修次数来衡量。由于可能无法在现有的登记处中记录闭合复位,因此脱位的确切发生率可能难以确定。本研究的目的是确定原发性 THA 后髋关节脱位(翻修和闭合复位)的“真实”累积发生率,次要目的是确定脱位的危险因素。

方法

我们从丹麦髋关节置换登记处确定了 2010 年至 2014 年间因原发性骨关节炎而进行的 31105 例原发性 THA,并进行了 2 年的随访。通过从丹麦国家患者登记处提取来确定脱位。我们认为与诊断和手术代码匹配的代码是正确的,而与诊断和手术代码不匹配的代码则通过对患者病历的全面、全国性审查进行审查。使用多因素逻辑回归分析对危险因素进行分析,并以 95%置信区间(CI)表示比值比(OR)。

结果

我们对患者病历的审查发现,1079 例 THA 中有 1861 例脱位,这相当于 2 年的累积发生率为 3.5%(CI=3.3%至 3.7%)。与仅通过行政登记数据正确编码的脱位相比,这增加了 50%。与 65 至 75 岁的患者相比,<65 岁的患者脱位风险较低(OR=0.70;CI=0.59 至 0.83),而>75 岁的患者脱位风险较高(OR=1.32;CI=1.14 至 1.52)。与 65 至 75 岁的患者相比,男性(OR=0.86;CI=0.75 至 0.98)、骨水泥固定(OR=0.71;CI=0.58 至 0.87)和外侧入路(OR=0.28;CI=0.16 至 0.49)都与较低的风险相关。与 36 毫米头相比,32 毫米头的脱位风险更高(OR=1.27;CI=1.10 至 1.46),而双动杯则降低了脱位风险(OR=0.13;CI=0.05 至 0.36)。

结论

我们发现,2010 年至 2014 年间在丹麦进行的原发性 THA 术后 2 年内,脱位的“真实”累积发生率为 3.5%。年龄、性别、美国麻醉医师协会(ASA)评分、头大小和类型、固定方法和手术入路是脱位的独立显著因素。需要全面的搜索算法来识别所有脱位,以便在国家登记处准确报告这种并发症。

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