使用舒更葡糖钠治疗罗库溴铵诱导的过敏反应——一例报告
Treatment of rocuronium-induced anaphylaxis using sugammadex - A case report.
作者信息
Kim Sun-Min, Oh Sei-Hoon, Ryu Seung-Ah
机构信息
Department of Anesthesiology and Pain Medicine, Seoul Medical Center, Seoul, Korea.
出版信息
Anesth Pain Med (Seoul). 2021 Jan;16(1):56-59. doi: 10.17085/apm.20074. Epub 2020 Dec 17.
BACKGROUND
Perioperative anaphylaxis is a life-threatening clinical condition characterized by severe respiratory and cardiovascular manifestations. Neuromuscular blocking agents are the most common cause of anaphylaxis during anesthesia.
CASE
We report a case of rocuronium-induced anaphylaxis treated with sugammadex. A 75-year-old female was scheduled to undergo spinal surgery. She had no history of allergies. After the injection of rocuronium, she developed hypotension and tachycardia, and skin rashes and urticaria appeared. The patient received sugammadex to delay the operation, and her vital signs were stabilized. On the 76th postoperative day, we performed intradermal tests for rocuronium, propofol, and cefazolin. Diluted rocuronium alone induced 14 mm of flare and 8 mm of wheal within 5 min, both of which disappeared within 15 min after the intradermal injection.
CONCLUSIONS
Sugammadex is a useful rocuronium antagonist that can be used to treat rocuronium-induced anaphylaxis.
背景
围手术期过敏反应是一种危及生命的临床状况，其特征为严重的呼吸和心血管表现。神经肌肉阻滞剂是麻醉期间过敏反应最常见的原因。
病例
我们报告一例用舒更葡糖治疗罗库溴铵诱导的过敏反应的病例。一名75岁女性计划接受脊柱手术。她无过敏史。注射罗库溴铵后，她出现低血压和心动过速，并出现皮疹和荨麻疹。患者接受舒更葡糖以推迟手术，其生命体征得以稳定。术后第76天，我们对罗库溴铵、丙泊酚和头孢唑林进行了皮内试验。仅稀释的罗库溴铵在5分钟内引起了14毫米的风团和8毫米的红晕，两者在皮内注射后15分钟内均消失。
结论
舒更葡糖是一种有用的罗库溴铵拮抗剂，可用于治疗罗库溴铵诱导的过敏反应。
Zotero 插件