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食源性中毒致儿童后可逆性脑病综合征 1 例报告

Posterior reversible encephalopathy syndrome induced by food poisoning in a pediatric patient: a case report.

机构信息

Department of Pediatric Neurology, First Hospital of Jilin University, Changchun, China.

Department of Cardiology, Northeast International Hospital, Changchun, China.

出版信息

J Int Med Res. 2020 Dec;48(12):300060520980201. doi: 10.1177/0300060520980201.

Abstract

Posterior reversible encephalopathy syndrome (PRES) can develop in patients following exposure to multiple triggers, including blood pressure fluctuations, kidney diseases, immunosuppressive agents, chemotherapy, or autoimmune disorders. However, to the best of our knowledge, the development of PRES secondary to food poisoning has not been previously reported, especially in a pediatric patient. Here, we report a 13-year-old boy who presented with PRES following the consumption of palmatum (a chicken feet dish). The patient presented with headache, vomiting, and altered consciousness. Neuroimaging findings revealed white matter hyperintensities in a bilateral, symmetrical, and parieto-occipital pattern. The patient was diagnosed with PRES and was managed with fluid expansion and a short-term mannitol regimen (1 g/kg every 12 hours for 3 days). Neuroimaging findings returned to normal at 8 days after admission. Food poisoning may therefore be a new possible trigger for PRES. A timely PRES diagnosis is recommended to prevent possible central nervous system complications.

摘要

后部可逆性脑病综合征 (PRES) 可发生于暴露于多种诱因的患者中,包括血压波动、肾脏疾病、免疫抑制剂、化疗或自身免疫性疾病。然而,据我们所知,先前没有报道过食物中毒引起的 PRES,特别是在儿科患者中。在这里,我们报告了一例 13 岁男孩,他在食用鸡爪(palmatum)后出现 PRES。患者表现为头痛、呕吐和意识改变。神经影像学发现显示双侧、对称和顶枕部的脑白质高信号。该患者被诊断为 PRES,并接受了液体扩张和短期甘露醇治疗方案(1 g/kg,每 12 小时一次,共 3 天)。入院后 8 天神经影像学发现恢复正常。因此,食物中毒可能是 PRES 的一个新的可能诱因。建议及时诊断 PRES,以预防可能的中枢神经系统并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0ce/7758666/7f67cd6bcaa7/10.1177_0300060520980201-fig1.jpg

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