米兰超声标准在评估溃疡性结肠炎的疾病活动度方面是准确的：外部验证。
Milan ultrasound criteria are accurate in assessing disease activity in ulcerative colitis: external validation.
机构信息
Department of Gastroenterology, Humanitas Clinical and Research Center - IRCCS, Milan, Italy.
Department of Biomedical Sciences, Humanitas University, Milan, Italy.
出版信息
United European Gastroenterol J. 2021 May;9(4):438-442. doi: 10.1177/2050640620980203. Epub 2021 Feb 16.
INTRODUCTION
The aim of this study was to provide an external validation of bowel ultrasound (US) predictors of activity in ulcerative colitis (UC) and quantitative Milan Ultrasound Criteria (MUC).
METHODS
Forty-three consecutive patients with UC (16 in endoscopic remission and 27 with endoscopic activity) underwent bowel US and colonoscopy in a tertiary referral inflammatory bowel disease unit.
RESULTS
An MUC score >6.2 discriminated patients with active versus non-active UC with a sensitivity of 0.85 (95% confidence interval (CI) 0.66-0.96), specificity of 0.94 (95% CI 0.70-0.99) and an area under the curve of 0.902 (95% CI 0.772-0.971) in complete agreement with the derivation study.
CONCLUSION
The external validation of MUC confirms that it is an accurate tool for assessing disease activity in patients with UC.
简介
本研究旨在对溃疡性结肠炎（UC）的肠超声（US）预测指标和定量米兰超声标准（MUC）进行外部验证。
方法
在一个三级转诊炎症性肠病单位，43 例连续的 UC 患者（16 例内镜缓解，27 例内镜活动）接受了肠 US 和结肠镜检查。
结果
MUC 评分>6.2 可区分活动期与非活动期 UC 患者，其敏感性为 0.85（95%置信区间（CI）0.66-0.96），特异性为 0.94（95%CI 0.70-0.99），曲线下面积为 0.902（95%CI 0.772-0.971），与原始研究完全一致。
结论
MUC 的外部验证证实，它是评估 UC 患者疾病活动度的一种准确工具。
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