专利中的紫胶红：一种具有广泛生物活性和工业潜力的化合物。
Patents on Violacein: A Compound with Great Diversity of Biological Activities and Industrial Potential.
机构信息
Laboratory of Urogenital Carcinogenesis and Immunotherapy, Biology Institute, Department of Structural and Functional Biology, University of Campinas, Campinas, Sao Paulo, Brazil.
Laboratory of Tropical Diseases, Institute of Biology, Department of Genetic, Evolution, Microbiology and Immunology. University of Campinas, Campinas, Sao Paulo, Brazil.
出版信息
Recent Pat Biotechnol. 2021 Oct 4;15(2):102-111. doi: 10.2174/2213476X07666201221111655.
BACKGROUND
This review outlines the current impact of violacein-derivative materials in several technological areas through patents.
METHODS
A comprehensive examination of patent databases on violacein demonstrated the relevance of this pigment, as well as the pertinent topics related to its technological development in order to obtain adaptable new pharmaceuticals, cosmetics, and new quality fiber materials, together with other applications of violacein in different areas.
RESULTS
At present, there is no efficient and economical technique for violacein preparation at the industrial scale. Many attempts have been made, but none have overcome the challenge of being an effective and inexpensive process. However, some potential applications of violacein in fields such as biomedicine make the pigment worthy of continuous investigation. In particular, violacein patents covering biosynthesis for different applications have been reported recently.
CONCLUSION
Violacein has been used as a unique pigment in distinct specialty areas, such as in medical and industrial fields. This review of patents provides an update on violacein innovations that are useful for researchers working in the expanding and interesting field of biotechnology with natural pigments.
背景
本综述通过专利概述了目前色杆菌素衍生材料在多个技术领域的影响。
方法
对色杆菌素专利数据库进行了全面审查，展示了该色素的相关性，以及与其技术开发相关的相关主题，以获得适应性强的新药物、化妆品和新型优质纤维材料，以及色杆菌素在不同领域的其他应用。
结果
目前，在工业规模上还没有高效、经济的色杆菌素制备技术。虽然已经进行了许多尝试，但都未能克服有效且廉价的工艺这一挑战。然而，色杆菌素在生物医药等领域的一些潜在应用使得该色素值得持续研究。特别是，最近报道了涵盖不同应用的生物合成的色杆菌素专利。
结论
色杆菌素已被用作某些特殊领域（如医学和工业领域）的独特色素。本专利综述为从事生物技术领域天然色素研究的研究人员提供了有关色杆菌素创新的最新信息。
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