Rutgers J L, Scully R E
Department of Pathology, Harvard Medical School, Boston, Massachusetts.
Cancer. 1988 Jan 15;61(2):340-8. doi: 10.1002/1097-0142(19880115)61:2<340::aid-cncr2820610225>3.0.co;2-u.
Ovarian mucinous cystadenomas of borderline malignancy that contain foci of intestinal differentiation are well recognized. Borderline tumors lined by mucinous epithelium of endocervical type and characterized by papillae architecturally similar to those of serous borderline tumors, however, have not been described in the literature. We have studied 30 tumors of this type. The patients averaged 34 years of age. Forty percent of the tumors were synchronously bilateral and 30% were associated with endometriosis. Four tumors were complicated by peritoneal implants, one by both peritoneal implants and lymph node metastasis and one by lymph node metastasis alone. No patient had pseudomyxoma peritonei. Follow-up information was available on all the patients for a mean interval of 3.7 years. In two cases tumors developed in the conserved contralateral ovary; no deaths occurred. These tumors have important clinical and pathologic differences from mucinous borderline tumors with intestinal differentiation, but have many similarities to mixed-epithelial borderline tumors of Mullerian type.
含有肠化生灶的交界性恶性卵巢黏液性囊腺瘤已广为人知。然而，文献中尚未描述过以内宫颈型黏液上皮为衬里、在结构上具有与浆液性交界性肿瘤相似乳头的交界性肿瘤。我们研究了30例此类肿瘤。患者平均年龄为34岁。40%的肿瘤为双侧同时发生，30%与子宫内膜异位症相关。4例肿瘤并发腹膜种植，1例同时有腹膜种植和淋巴结转移，1例仅有淋巴结转移。无患者发生腹膜假黏液瘤。所有患者均有平均3.7年的随访信息。2例患者在保留的对侧卵巢发生肿瘤；无死亡病例。这些肿瘤与具有肠化生的黏液性交界性肿瘤有重要的临床和病理差异，但与苗勒管型混合上皮交界性肿瘤有许多相似之处。
