Rutgers J L, Scully R E
Department of Pathology, Harvard Medical School, Boston, Massachusetts.
Cancer. 1988 Feb 1;61(3):546-54. doi: 10.1002/1097-0142(19880201)61:3<546::aid-cncr2820610321>3.0.co;2-i.
Borderline tumors with papillae that are architecturally similar to those of serous tumors but with a lining of more than one mullerian cell type have not been well characterized in in the literature. We have studied 36 such tumors. The patients averaged 35 years of age. Twenty-two percent of the tumors were bilateral; all were confined to the ovaries as confirmed at operation. Fifty-three percent were associated with endometriosis. Follow-up information was available on 34 patients for a mean interval of 4.8 years. A tumor developed in the contralateral ovary in one patient 2 years after unilateral salpingo-oophorectomy. Three patients had pelvic recurrences between 7 months and 3 years, but all of them were successfully treated and none have died. These tumors differ clinically and pathologically from intestinal-type mucinous borderline tumors, but they have many similarities with mullerian mucinous borderline tumors and, to a lesser extent, with serous borderline tumors.
具有乳头结构的交界性肿瘤，其结构与浆液性肿瘤相似，但内衬有不止一种苗勒管细胞类型，这类肿瘤在文献中尚未得到充分描述。我们研究了36例此类肿瘤。患者平均年龄为35岁。22%的肿瘤为双侧性；经手术证实，所有肿瘤均局限于卵巢。53%的肿瘤与子宫内膜异位症相关。34例患者有随访信息，平均随访时间为4.8年。1例患者在单侧输卵管卵巢切除术后2年，对侧卵巢出现肿瘤。3例患者在7个月至3年之间出现盆腔复发，但均成功治疗，无一例死亡。这些肿瘤在临床和病理上与肠型黏液性交界性肿瘤不同，但与苗勒管黏液性交界性肿瘤有许多相似之处，并在较小程度上与浆液性交界性肿瘤相似。
