Department of Ophthalmology, Saitama Medical University, Iruma, Saitama Prefecture, Japan.
J Glaucoma. 2021 Jun 1;30(6):537-544. doi: 10.1097/IJG.0000000000001764.
This study showed the difference of monocular visual sensitivity between with and without background light given to the nontested fellow eyes in glaucoma patients. Monocular sensitivity measurements of the worse eyes with fellow eye's background light conditions should carefully be considered when assessing the impact of functional impairment in glaucoma patients.
The purpose of this study was to investigate the difference between monocular sensitivities measured with and without background light given to the nontested fellow eye in glaucoma patients using a new perimeter named "imo."
In this cross-sectional study, we examined 102 eyes of 51 patients (mean age, 65.1±14.9 y) with open-angle glaucoma who were affected with at least 1 significant point in the central 10 degrees. We conducted a routine ophthalmic examination and visual field testing using the Humphrey Field Analyzer 24-2 and 10-2 programs. The eyes were assigned to "better" and "worse" categories based on the visual acuity and central visual thresholding. Subsequently, we compared the central visual sensitivities with and without background light given to the nontested fellow eye.
The mean sensitivity (MS) in the central 5 points of the visual field of the worse eyes was better when measured with background light than without background light (P=0.037) given to the nontested fellow eye. No significant difference was seen among the MS in the visual field of the better eyes. After dividing the patients into low (n=25) and high sensitivity (n=26) groups, only the low sensitivity group in worse eyes had higher MS with background light than without background light (P<0.05) given to the nontested fellow eye.
Monocular sensitivities measured with background light given to the nontested fellow eye were higher than those without background light in the worse eye group of glaucoma patients. Monocular MS measurements of the worse eyes with fellow eye's background light conditions and their related indices should thus carefully be considered when assessing the impact of functional impairment in glaucoma patients.
本研究旨在使用新型周边视野计“imo”，研究青光眼患者未受检对侧眼给予背景光和不给予背景光时单眼敏感性的差异。
在这项横断面研究中，我们检查了 51 名（平均年龄，65.1±14.9 岁）开角型青光眼患者的 102 只眼，这些患者的中央 10 度内至少有 1 个显著点受影响。我们使用 Humphrey Field Analyzer 24-2 和 10-2 程序进行了常规眼科检查和视野测试。根据视力和中央视觉阈值，将眼分为“好眼”和“差眼”。随后，我们比较了未受检对侧眼给予和不给予背景光时的中央视觉敏感性。
差眼中央 5 个视野点的平均敏感度（MS）在给予背景光时优于不给予背景光（P=0.037）。好眼中视野的 MS 无显著差异。将患者分为低（n=25）和高（n=26）敏感性组后，只有差眼的低敏感性组给予背景光时的 MS 高于不给予背景光（P<0.05）。
青光眼患者差眼中给予背景光时的单眼敏感性高于不给予背景光时。因此，在评估青光眼患者的功能损害影响时，应仔细考虑差眼的单眼 MS 测量值及其相关指标，包括对侧眼的背景光条件。
