Department of Ophthalmology, Kindai University Faculty of Medicine.
Clinical Research Center, Kindai University Hospital, Osaka, Japan.
J Glaucoma. 2021 Jan 1;30(1):37-43. doi: 10.1097/IJG.0000000000001675.
A difference between monocular sensitivities measured with and without occlusion was observed in glaucoma. Monocular sensitivity without occlusion could have been affected differently by binocular interaction due to the sensitivity disparity between both eyes.
To investigate the influence of sensitivity disparity between both eyes on visual field results under binocular viewing in glaucoma.
Thirteen glaucoma patients tested by Humphrey Field Analyzer (HFA) and imo were reviewed retrospectively. On the basis of their HFA results, we defined the eye with a better HFA-MD as "the better eye" and the fellow eye with a worse HFA-MD as "the worse eye." Depending on the pointwise pattern deviation (PD) of both eyes, all evaluated test points were classified into 4 groups: normal PD in both eyes (N/N), normal PD in the better eye but abnormal in the worse eye (N/A), abnormal PD in the better eye but normal in the worse eye (A/N), and abnormal PD in both eyes (A/A). Using imo, which can measure sensitivity with and without occluding the nontested eye, the better eye's sensitivities with and without occlusion were compared in each group using weighted data. The weight was derived by applying the inverse probability weighting.
Monocular sensitivity without occlusion was higher than that with occlusion in N/N (P<0.01) and the opposite was observed in A/A (P<0.05). No significant sensitivity difference between both conditions was seen in N/A or A/N. In N/A, the points showing a higher sensitivity without occlusion decreased as the sensitivity difference between both eyes increased.
A difference between sensitivities measured with and without occlusion was observed in glaucoma. Owing to the sensitivity disparity between both eyes, monocular sensitivity without occlusion could have been affected differently by binocular interaction.
在青光眼患者中，观察到用和不用眼罩测量的单眼敏感性之间存在差异。由于双眼之间的敏感性差异，单眼无眼罩敏感性可能因双眼相互作用而受到不同影响。
研究双眼敏感性差异对视功能检查在青光眼患者双眼检查中的影响。
回顾性分析 13 例经 Humphrey 视野分析仪（HFA）和 imo 检查的青光眼患者。根据 HFA 结果，我们将 MD 较好的眼定义为“优势眼”，MD 较差的眼定义为“劣势眼”。根据双眼的点值模式偏差（PD），将所有评估的测试点分为 4 组：双眼 PD 正常（N/N）、优势眼 PD 正常而劣势眼 PD 异常（N/A）、优势眼 PD 异常而劣势眼 PD 正常（A/N）和双眼 PD 异常（A/A）。使用 imo，它可以测量未遮盖眼的敏感度，我们对每组患者分别采用加权数据比较双眼优势眼的遮盖和不遮盖时的敏感度。权重是通过应用逆概率加权得出的。
在 N/N 组中，双眼 PD 正常的患者单眼不遮盖时的敏感性高于遮盖时（P<0.01），而在 A/A 组中则相反（P<0.05）。在 N/A 或 A/N 组中，两种条件下的敏感性没有显著差异。在 N/A 组中，随着双眼敏感性差异的增大，不遮盖时敏感性更高的点减少。
在青光眼患者中，用和不用眼罩测量的单眼敏感性之间存在差异。由于双眼之间的敏感性差异，单眼无眼罩敏感性可能因双眼相互作用而受到不同影响。
