Böckers M, Keller E, Bork K
Hautklinik, Universität Mainz.
Dtsch Med Wochenschr. 1988 Jan 8;113(1):20-1. doi: 10.1055/s-2008-1067586.
A 58-year-old woman underwent regional intra-arterial chemotherapy for hepatic metastases of a malignant melanoma, because at the time no other organ metastasis was demonstrable. Dacarbazine was injected as a bolus on five successive days, four weeks apart, after which there were several days of fever and the urinary melanogen test became positive. At first the patient clearly improved and was again able to walk. But four months after the start of treatment she died in a hepatic coma.
一名58岁女性因恶性黑色素瘤肝转移接受了区域动脉内化疗，因为当时未发现其他器官转移。在相隔四周的连续五天里，大剂量注射达卡巴嗪，之后出现了几天发热，尿黑素原试验呈阳性。起初患者明显好转，又能行走了。但治疗开始四个月后，她死于肝昏迷。
