Clinic of Gastroenterology and Hepatology, Clinical Center of Serbia, Belgrade, Serbia.
Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Dis Markers. 2020 Nov 28;2020:8523205. doi: 10.1155/2020/8523205. eCollection 2020.
There was a high statistically significant difference between IBD patients and controls in levels of hepcidin ( < 0.01). Namely, serum hepcidin levels were significantly higher in the control group. There was no statistically significant correlation of serum hepcidin with CRP, Mayo score, or CDAI, respectively ( > 0.05). However, we have found a statistically significant negative correlation of sTfR and TIBC with hepcidin ( < 0.01).
Results of our study suggest that hepcidin is a reliable marker of IDA in patients with IBD, and it could be used in routine clinical practice when determining adequate therapy in these patients.
IBD 患者和对照组之间的铁调素水平存在显著统计学差异（<0.01）。即对照组的血清铁调素水平显著更高。血清铁调素与 CRP、Mayo 评分或 CDAI 之间分别无显著相关性（>0.05）。然而，我们发现 sTfR 和 TIBC 与铁调素之间存在显著负相关（<0.01）。
我们的研究结果表明，铁调素是 IBD 患者 IDA 的可靠标志物，可在这些患者确定适当治疗时用于常规临床实践。
