Department of Urology, The University of Jordan, Amman, Jordan.
Cairo University, Cairo, Egypt.
Adv Ther. 2021 Feb;38(2):1155-1167. doi: 10.1007/s12325-020-01588-4. Epub 2020 Dec 22.
Estimate the prevalence of symptoms suggestive of overactive bladder (OAB) in women living in the Middle East to describe their demographic characteristics and explore treatment-seeking behavior.
Cross-sectional, population-based survey of women aged ≥ 40 years resident in Algeria, Jordan, Lebanon or Egypt. Respondents were recruited using computer-assisted telephone interview over approximately 4 months. Eligible respondents were asked to complete the OAB-V8, a validated questionnaire that explores the extent of bother from the key symptoms of OAB without clinical investigations. In addition, information regarding demographics, comorbidities and treatment behavior was collected, and respondents were stratified by age.
A total of 2297 eligible women agreed to participate. Mean age was 54 ± 10 years; over half (59.3%) were aged 40-55 years. Overall, 53.8% of eligible women had symptoms suggestive of OAB (Jordan 58.5%; Egypt 57.5%; Algeria 49.9%; Lebanon 49.0%), with over 90% also reporting symptoms of urinary incontinence. Only 13.0% of women with symptoms suggestive of OAB were currently receiving treatment, while most (74.3%) had never been treated; these data were consistent across country and age categories. Among the untreated subgroup, almost half (48.7%) reported they were 'not bothered by symptoms,' while 8.4% considered OAB to be 'part of normal aging' and 4.7% did not know it was treatable.
A high prevalence of symptoms suggestive of OAB was observed, and the majority had symptoms of urinary incontinence. Despite the high prevalence, most women had never received treatment. Considering the potential significant impact of OAB symptoms on health, quality of life and productivity, these findings highlight an unmet medical need in the population studied. Strategies to improve treatment-seeking behavior (e.g., through education and tackling the stigma associated with OAB symptoms) may improve the diagnosis, management and health outcomes of women with OAB in the Middle East.
估计居住在中东的女性中膀胱过度活动症(OAB)症状的患病率,描述其人口统计学特征,并探讨治疗寻求行为。
对年龄≥40 岁的居住在阿尔及利亚、约旦、黎巴嫩或埃及的女性进行横断面、基于人群的调查。使用计算机辅助电话访谈在大约 4 个月内招募受访者。合格的受访者被要求完成 OAB-V8,这是一个经过验证的问卷,用于探索 OAB 关键症状的困扰程度,而无需进行临床检查。此外,还收集了人口统计学、合并症和治疗行为的信息,并按年龄分层。
共有 2297 名符合条件的女性同意参加。平均年龄为 54±10 岁;超过一半(59.3%)年龄在 40-55 岁之间。总体而言,53.8%的合格女性有 OAB 症状(约旦 58.5%;埃及 57.5%;阿尔及利亚 49.9%;黎巴嫩 49.0%),超过 90%的女性也有尿失禁症状。仅有 13.0%有 OAB 症状的女性正在接受治疗,而大多数(74.3%)从未接受过治疗;这些数据在国家和年龄组之间是一致的。在未治疗亚组中,近一半(48.7%)表示他们“不受症状困扰”,而 8.4%认为 OAB 是“正常衰老的一部分”,4.7%不知道它可以治疗。
观察到 OAB 症状的高患病率,大多数女性有尿失禁症状。尽管患病率高,但大多数女性从未接受过治疗。考虑到 OAB 症状对健康、生活质量和生产力的潜在重大影响,这些发现突显了所研究人群中的未满足的医疗需求。改善治疗寻求行为的策略(例如,通过教育和解决与 OAB 症状相关的耻辱感)可能会改善中东地区 OAB 女性的诊断、管理和健康结果。