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美国膀胱过度活动症对工作效率的影响:来自EpiLUTS的结果

Impact of overactive bladder on work productivity in the United States: results from EpiLUTS.

作者信息

Sexton Chris C, Coyne Karin S, Vats Vasudha, Kopp Zoe S, Irwin Debra E, Wagner Todd H

机构信息

Center for Health Outcomes Research, United BioSource Corporation, 7101 Wisconsin Ave, Ste 600, Bethesda, MD 20814, USA.

出版信息

Am J Manag Care. 2009 Mar;15(4 Suppl):S98-S107.

Abstract

OBJECTIVE

Little research has focused on the impact of overactive bladder (OAB) on work productivity. Consequently, the impact of OAB and other lower urinary tract symptoms (LUTS) on work productivity was evaluated in employed men and women aged 40 to 65 in the United States.

STUDY DESIGN

Data from a population-based, cross-sectional Internet survey were used to examine the impact of OAB symptoms on work productivity. US participants aged 40 to 65 working full- or part-time were included in the analysis. Participants were asked about the incidence of OAB and other LUTS and a series of questions about work productivity.

METHODS

Descriptive statistics and linear and logistic regressions were used to evaluate outcome differences for men and women by the OAB groups of no/minimal symptoms, continent OAB, and incontinent OAB.

RESULTS

The response rate was 60%, and a total of 2876 men and 2820 women were analyzed. Men and women with incontinent OAB reported the lowest levels of work productivity and highest rates of daily work interference. Storage symptoms associated with OAB were most consistently associated with work productivity outcomes; however, significant associations were also found for other storage, voiding, and postmicturition LUTS.

CONCLUSION

In this large US population-based study, OAB was highly prevalent and was associated with lower levels of work productivity. These findings add to the literature documenting the burden of OAB and other LUTS, underscoring the need for increased screening and treatment.

摘要

目的

很少有研究关注膀胱过度活动症(OAB)对工作效率的影响。因此,在美国40至65岁的在职男性和女性中,评估了OAB及其他下尿路症状(LUTS)对工作效率的影响。

研究设计

基于人群的横断面网络调查数据被用于研究OAB症状对工作效率的影响。分析纳入了年龄在40至65岁的美国全职或兼职工作参与者。参与者被问及OAB及其他LUTS的发生率以及一系列关于工作效率的问题。

方法

使用描述性统计以及线性和逻辑回归,按无/最小症状、无尿失禁的OAB和有尿失禁的OAB组评估男性和女性的结果差异。

结果

回复率为60%,共分析了2876名男性和2820名女性。有尿失禁的OAB的男性和女性报告的工作效率水平最低,日常工作干扰率最高。与OAB相关的储尿症状与工作效率结果的相关性最为一致;然而,在其他储尿、排尿和排尿后LUTS方面也发现了显著相关性。

结论

在这项基于美国大量人群的研究中,OAB非常普遍,且与较低的工作效率相关。这些发现增加了记录OAB和其他LUTS负担的文献,强调了加强筛查和治疗的必要性。

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