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[阿昔洛韦联合胸腺肽治疗生殖器疱疹患者的心理护理及其对不良反应发生率的影响]

[Psychological nursing for genital herpes patients receiving acyclovir plus thymosin and its effect on the incidence of adverse reactions].

作者信息

Zhang Xing-Hua, Lu Yan, Sun Li-Li, Sun Zi-Xue

机构信息

Department of Reproductive Medicine, Henan Provincial Hospital of Traditional Chinese Medicine, Zhengzhou, Henan 450002, China.

出版信息

Zhonghua Nan Ke Xue. 2020 May;26(5):436-440.

Abstract

OBJECTIVE

To explore the application of psychological nursing in patients with genital herpes receiving acyclovir combined with thymosin and its effect on the incidence of adverse reactions.

METHODS

A total of 160 patients with genital herpes treated with acyclovir plus thymosin in our hospital from January 2016 to December 2018 were randomly allocated to receive conventional nursing (the control group, n = 80) and psychological nursing (the trial group, n = 80). Self-rating Anxiety Scale (SAS) and Self-rating Depression Scale (SDS) were used to evaluate the anxiety and depression of the patients, and comparisons were made between the two groups of patients in their SAS and SDS scores, the incidence of adverse reactions and their satisfaction with nursing intervention.

RESULTS

After nursing intervention, the patients of the trial group, compared with the controls, showed significantly lower SAS scores (39.05 ± 2.97 vs 45.71 ± 3.36, P < 0.01), SDS scores (41.74 ± 2.86 vs 47.28 ± 3.95, P < 0.01), and incidence of adverse reactions (22.50% vs 47.50%, P < 0.05), but a markedly higher rate of satisfaction with nursing intervention (95.00% vs 77.5%, P < 0.01).

CONCLUSIONS

Psychological nursing can reduce the incidence of adverse reactions in genital herpes patients receiving acyclovir combined with thymosin and meanwhile improve the mental status of the patients by alleviating their anxiety and depression.

摘要

目的

探讨心理护理在接受阿昔洛韦联合胸腺肽治疗的生殖器疱疹患者中的应用及其对不良反应发生率的影响。

方法

选取2016年1月至2018年12月在我院接受阿昔洛韦加胸腺肽治疗的160例生殖器疱疹患者,随机分为常规护理组(对照组,n = 80)和心理护理组(试验组,n = 80)。采用焦虑自评量表(SAS)和抑郁自评量表(SDS)评估患者的焦虑和抑郁情况,并比较两组患者的SAS和SDS评分、不良反应发生率以及对护理干预的满意度。

结果

护理干预后,试验组患者的SAS评分(39.05±2.97 vs 45.71±3.36,P < 0.01)、SDS评分(41.74±2.86 vs 47.28±3.95,P < 0.01)和不良反应发生率(22.50% vs 47.50%,P < 0.05)均显著低于对照组,但对护理干预的满意度明显高于对照组(95.00% vs 77.5%,P < 0.01)。

结论

心理护理可降低接受阿昔洛韦联合胸腺肽治疗的生殖器疱疹患者的不良反应发生率,同时通过缓解患者的焦虑和抑郁情绪改善其心理状态。

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