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右美托咪定戒断综合征与阿片类药物敏感性

Dexmedetomidine withdrawal syndrome and opioid sensitivity.

作者信息

Ferguson Lana, Hooper Stacey

机构信息

Palliative Care, Waikato District Health Board, Hamilton, New Zealand

Palliative Care, Waikato District Health Board, Hamilton, New Zealand.

出版信息

BMJ Support Palliat Care. 2023 Oct;13(e1):e105-e107. doi: 10.1136/bmjspcare-2020-002705. Epub 2020 Dec 22.

DOI:10.1136/bmjspcare-2020-002705
PMID:33355169
Abstract

This case report describes the use of dexmedetomidine for refractory cancer pain management in a patient with significant pelvic disease due to metastatic urothelial cancer. Specifically, the management of increased opioid sensitivity secondary to dexmedetomidine is discussed. Further, the phenomenon of dexmedetomidine withdrawal syndrome and our management of this is addressed.

摘要

本病例报告描述了右美托咪定在一名因转移性尿路上皮癌导致严重盆腔疾病的患者中用于难治性癌痛管理的情况。具体讨论了右美托咪定引起的阿片类药物敏感性增加的处理。此外，还探讨了右美托咪定戒断综合征现象及其处理方法。

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Dexmedetomidine withdrawal syndrome and opioid sensitivity.右美托咪定戒断综合征与阿片类药物敏感性
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Subcutaneous dexmedetomidine infusions to treat or prevent drug withdrawal in infants and children.皮下输注右美托咪定用于治疗或预防婴幼儿药物戒断反应。
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Dexmedetomidine for opioid and benzodiazepine withdrawal in pediatric patients.右美托咪定用于儿科患者阿片类药物和苯二氮䓬类药物戒断。
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Prolonged dexmedetomidine infusion as an adjunct in treating sedation-induced withdrawal.持续输注右美托咪定作为治疗镇静诱导戒断的辅助手段。
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引用本文的文献

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Dexmedetomidine only regimen for long-term sedation is associated with reduced vasopressor requirements in septic shock patients: A retrospective cohort study from MIMIC-IV database.脓毒性休克患者长期镇静使用右美托咪定单药方案与血管升压药需求减少相关：一项来自MIMIC-IV数据库的回顾性队列研究
Front Med (Lausanne). 2023 Feb 27;10:1107251. doi: 10.3389/fmed.2023.1107251. eCollection 2023.