Leonard D. Schaeffer Center for Health Policy and Economics, University of Southern California, Los Angeles.
Sol Price School of Public Policy, University of Southern California, Los Angeles.
JAMA Psychiatry. 2021 Mar 1;78(3):311-319. doi: 10.1001/jamapsychiatry.2020.3995.
Racial/ethnic disparities in health care use and clinical outcomes for behavioral health disorders, including psychosis, are well documented, but less is known about these disparities during the period leading up to first-episode psychosis (FEP).
To describe the racial/ethnic disparities in behavioral health care use and prescription drug use of children and young adults before the diagnosis of FEP.
DESIGN, SETTING, AND PARTICIPANTS: An observational cohort study was conducted using medical and prescription drug claims from January 1, 2007, to September 30, 2015, obtained from Optum's deidentified Clinformatics Data Mart Database, a commercial claims database augmented with race/ethnicity and socioeconomic variables. Data analysis was performed from February 6, 2018, to October 10, 2020. First-episode psychosis was determined by the presence of psychosis diagnoses on claims for at least 1 hospitalization or 2 outpatient events, with a continuous enrollment requirement of at least 2 years before the first diagnosis. Participants included 3017 Black, Hispanic, or White patients who were continually enrolled in commercial insurance plans and received an FEP diagnosis between the ages of 10 and 21 years.
Race/ethnicity was determined from a commercial claims database. Rates of inpatient admission, emergency department presentation, and outpatient visits (including psychotherapy), behavioral health disorder diagnoses, and antipsychotic/antidepressant prescription fills were determined for the year before FEP. Race/ethnicity was also obtained from Optum's claims database. With use of multivariable logistic regression, results were adjusted for covariates including estimated household income, age, sex, and geographic division in the US.
Of the 3017 patients with FEP, 643 Black or Hispanic patients (343 [53.3%] Black, 300 [46.7%] Hispanic, 324 [50.4%] male, mean [SD] age, 17.2 [2.76] years) were less likely than 2374 White patients (1210 [51.0%] male, mean age, 17.0 [2.72] years) to receive comorbid behavioral health disorder diagnoses in the year before the diagnosis of FEP (410 [63.8%] vs 1806 [76.1%], χ2 = 39.3; P < .001). Except for emergency care, behavioral health care use rates were lower in Black and Hispanic patients vs White patients (424 [65.9%] vs 1868 [78.7%]; χ2 = 45.0; P < .001), particularly for outpatient visits with behavioral health care professionals (232 [36.1%] vs 1236 [52.1%]; χ2 = 51.7; P < .001). After adjustment for socioeconomic covariates, behavioral health care use rates (68.9% vs 79.2%; P < .001), outpatient visits with behavioral health professionals (37.7% vs 51.2%; P < .001), and other outcomes remained significantly lower for Black and Hispanic patients vs White patients.
The results of this study extend existing research findings of well-known racial/ethnic disparities in the population of patients who are diagnosed with FEP. These differences were apparent in young patients with continuous commercial health insurance and after controlling for household income. Providing equal access to preventive outpatient behavioral health care may increase opportunities for timely detection of psychotic symptoms and early intervention and improve differential outcomes after FEP.
种族/民族在行为健康障碍(包括精神病)的医疗保健使用和临床结果方面的差异得到了充分证明,但在首次精神病发作(FEP)之前的这段时间内,这些差异的了解较少。
描述 FEP 前儿童和青年行为保健使用和处方药使用的种族/民族差异。
设计、设置和参与者:使用从 2007 年 1 月 1 日至 2015 年 9 月 30 日从 Optum 的匿名 Clinformatics Data Mart 数据库中获得的医疗和处方药索赔进行了一项观察性队列研究,该商业索赔数据库通过种族/民族和社会经济变量进行了扩充。数据分析于 2018 年 2 月 6 日至 2020 年 10 月 10 日进行。首次精神病发作通过至少 1 次住院或 2 次门诊事件的精神病诊断来确定,连续登记至少 2 年是首次诊断的要求。参与者包括 3017 名黑人、西班牙裔或白人患者,他们持续参加商业保险计划,并在 10 至 21 岁之间被诊断为 FEP。
种族/民族从商业索赔数据库中确定。在 FEP 前一年确定了住院率、急诊科就诊率和门诊就诊率(包括心理治疗)、行为健康障碍诊断和抗精神病/抗抑郁处方药配药率。Optum 的索赔数据库也获得了种族/民族信息。使用多变量逻辑回归,结果根据估计的家庭收入、年龄、性别和美国地理分区等协变量进行了调整。
在 3017 名 FEP 患者中,643 名黑人或西班牙裔患者(343 名[53.3%]黑人,300 名[46.7%]西班牙裔,324 名[50.4%]男性,平均[SD]年龄,17.2 [2.76]岁)与 2374 名白人患者(1210 名[51.0%]男性,平均年龄,17.0 [2.72]岁)相比,在 FEP 诊断前一年接受合并行为健康障碍诊断的可能性较低(410 名[63.8%]与 1806 名[76.1%],χ²=39.3;P<.001)。除了急诊护理外,黑人患者和西班牙裔患者的行为保健使用率均低于白人患者(424 名[65.9%]与 1868 名[78.7%];χ²=45.0;P<.001),尤其是与行为健康专业人员的门诊就诊率(232 名[36.1%]与 1236 名[52.1%];χ²=51.7;P<.001)。在调整了社会经济协变量后,行为保健使用率(68.9%与 79.2%;P<.001)、与行为健康专业人员的门诊就诊率(37.7%与 51.2%;P<.001)和其他结果仍然明显低于黑人患者和西班牙裔患者。
本研究的结果扩展了现有关于 FEP 患者人群中众所周知的种族/民族差异的研究结果。这些差异在连续参加商业健康保险的年轻患者中很明显,并且在控制家庭收入后仍然存在。提供平等获得预防门诊行为保健的机会可能会增加及时发现精神病症状和早期干预的机会,并改善 FEP 后的差异结果。